Prognostic effect of implementation of the mass low-dose computed tomography lung cancer screening program: a hospital-based cohort study

被引:30
作者
Wu, Fu-Zong [1 ,2 ,3 ]
Huang, Yi-Luan [1 ,2 ,3 ]
Wu, Yun-Ju [1 ]
Tang, En-Kuei [4 ,5 ]
Wu, Ming-Ting [1 ,2 ,3 ]
Chen, Chi-Shen [6 ]
Lin, Yun-Pei [1 ,2 ,3 ]
机构
[1] Kaohsiung Vet Gen Hosp, Dept Radiol, Kaohsiung, Taiwan
[2] Natl Yang Ming Univ, Fac Med, Sch Med, Taipei, Taiwan
[3] Natl Yang Ming Univ, Inst Clin Med, Taipei, Taiwan
[4] Kaohsiung Vet Gen Hosp, Dept Surg, Kaohsiung, Taiwan
[5] Shu Zen Jr Coll Med & Management, Dept Nursing, Kaohsiung, Taiwan
[6] Kaohsiung Vet Gen Hosp, Phys Examinat Ctr, Kaohsiung, Taiwan
关键词
hospital-based cancer registry; low-dose computed tomography; lung cancer; mortality rate; screening; CT; POPULATION; NODULES; GUIDELINES; MANAGEMENT; STATEMENT; MORTALITY; RISK;
D O I
10.1097/CEJ.0000000000000569
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Low-dose computed tomography lung cancer screening aims to detect early-stage lung cancers in order to decrease the incidence of advanced-stage lung cancers and to reduce lung cancer mortality. We analyzed the time trends of lung cancer stage distribution and mortality rates after the gradual implementation of the low-dose computed tomography lung cancer screening in a hospital-based cohort. Using the hospital-based cancer registry data on lung cancer number and death from 2007 to 2014, we aim to evaluate the trends in stage distribution and mortality rate after the gradual implementation of low-dose computed tomography lung cancer screening program over recent years. From 2007 to 2014, overall 2542 cases of lung cancers were diagnosed according to hospital-based cancer registry. For the 1-year mortality rate, the mortality rate decreased gradually from 48.16 to 37.04% between 2007 and 2014. For the 5-year mortality rate, the mortality rate decreased gradually from 88.49 to 69.44% between 2007 and 2014. There was a gradual decrease in stage IV lung cancer with the corresponding sharp increase in stage I early lung cancer after following the implementation of the large volume of the low-dose computed tomography examination between the years 2011 and 2014. In conclusion, these results suggest that the gradual implementation of low-dose computed tomography lung screening program could lead to a remarkable decrease in lung cancer mortality and a remarkable stage shift in the trend over time in this hospital-based cohort.
引用
收藏
页码:445 / 451
页数:7
相关论文
共 32 条
[1]   Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening [J].
Aberle, Denise R. ;
Adams, Amanda M. ;
Berg, Christine D. ;
Black, William C. ;
Clapp, Jonathan D. ;
Fagerstrom, Richard M. ;
Gareen, Ilana F. ;
Gatsonis, Constantine ;
Marcus, Pamela M. ;
Sicks, JoRean D. .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (05) :395-409
[2]  
[Anonymous], 2012, REP AD SMOK BEH SURV
[3]  
[Anonymous], 2007, TAIW CANC REG CRAR, P2007
[4]   Evaluating Shared Decision Making for Lung Cancer Screening [J].
Brenner, Alison T. ;
Malo, Ted L. ;
Margolis, Marjorie ;
Lafata, Jennifer Elston ;
James, Shynah ;
Vu, Maihan B. ;
Reuland, Daniel S. .
JAMA INTERNAL MEDICINE, 2018, 178 (10) :1311-1316
[5]   Comprehensive Analysis of the Incidence and Survival Patterns of Lung Cancer by Histologies, Including Rare Subtypes, in the Era of Molecular Medicine and Targeted Therapy A Nation-Wide Cancer Registry-Based Study From Taiwan [J].
Chang, Jeffrey S. ;
Chen, Li-Tzong ;
Shan, Yan-Shen ;
Lin, Sheng-Fung ;
Hsiao, Sheng-Yen ;
Tsai, Chia-Rung ;
Yu, Shu-Jung ;
Tsai, Hui-Jen .
MEDICINE, 2015, 94 (24)
[6]   Qualitative CT Criterion for Subsolid Nodule Subclassification: Improving Interobserver Agreement and Pathologic Correlation in the Adenocarcinoma Spectrum [J].
Chen, Po An ;
Huang, Eric P. ;
Shih, Lu Yang ;
Tang, En Kuei ;
Chien, Chu Chun ;
Wu, Ming Ting ;
Wu, Fu Zong .
ACADEMIC RADIOLOGY, 2018, 25 (11) :1439-1445
[7]   The IASLC Lung Cancer Staging Project: Background Data and Proposals for the Application of TNM Staging Rules to Lung Cancer Presenting as Multiple Nodules with Ground Glass or Lepidic Features or a Pneumonic Type of Involvement in the Forthcoming Eighth Edition of the TNM Classification [J].
Detterbeck, Frank C. ;
Marom, Edith M. ;
Arenberg, Douglas A. ;
Franklin, Wilbur A. ;
Nicholson, Andrew G. ;
Travis, William D. ;
Girard, Nicolas ;
Mazzone, Peter J. ;
Donington, Jessica S. ;
Tanoue, Lynn T. ;
Rusch, Valerie W. ;
Asamura, Hisao ;
Rami-Porta, Ramon .
JOURNAL OF THORACIC ONCOLOGY, 2016, 11 (05) :666-680
[8]   Modified Lung-RADS Improves Performance of Screening LDCT in a Population with High Prevalence of Non-smoking-related Lung Cancer [J].
Hsu, Hui-Ting ;
Tang, En-Kuei ;
Wu, Ming-Ting ;
Wu, Carol C. ;
Liang, Chia-Hao ;
Chen, Chi-Shen ;
Mar, Guang-Yuan ;
Lai, Ruay-Sheng ;
Wang, Jo-Ching ;
Wu, Chuan-Ling ;
Huang, Yi-Luan ;
Wu, Fu-Zong .
ACADEMIC RADIOLOGY, 2018, 25 (10) :1240-1251
[9]   Sex-associated differences in non-small cell lung cancer in the new era: Is gender an independent prognostic factor? [J].
Hsu, Li-Han ;
Chu, Nei-Min ;
Liu, Chia-Chuan ;
Tsai, Stella Y. C. ;
You, Dong-Ling ;
Ko, Jen-Sheng ;
Lu, Mei-Chun ;
Feng, An-Chen .
LUNG CANCER, 2009, 66 (02) :262-267
[10]   Propensity score analysis of lung cancer risk in a population with high prevalence of non-smoking related lung cancer [J].
Lin, Kuei-Feng ;
Wu, Hsiu-Fu ;
Huang, Wei-Chun ;
Tang, Pei-Ling ;
Wu, Ming-Ting ;
Wu, Fu-Zong .
BMC PULMONARY MEDICINE, 2017, 17