Chimeric antisense RNA derived from chromosomal translocation modulates target gene expression

被引：3
作者：
Sugimoto, Takumi [2 ]
Tomita, Akihiro [1 ]
Abe, Akihiro [3 ]
Iriyama, Chisako
Kiyoi, Hitoshi
Naoe, Tomoki
机构：
[1] Nagoya Univ, Grad Sch Med, Dept Hematol & Oncol, Showa Ku, Nagoya, Aichi 4668550, Japan
[2] Toyohashi Municipal Hosp, Dept Hematol & Oncol, Toyohashi, Aichi, Japan
[3] Fulita Hlth Univ, Sch Med, Dept Hematol, Toyoake, Aichi, Japan
来源：
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL | 2012年 / 97卷 / 08期
关键词：
chimeric transcript; antisense RNA; TAOK1; myelodysplastic syndrome; ACTIVATION; KINASE; FUSION; ETV6;
D O I：
10.3324/haematol.2011.057869
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：1278 / 1280
页数：3
相关论文
共 9 条
[1]   ETV6: A versatile player in leukemogenesis [J].
Bohlander, SK .
SEMINARS IN CANCER BIOLOGY, 2005, 15 (03) :162-174
[2]   A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling [J].
Draviam, Viji M. ;
Stegmeier, Frank ;
Nalepa, Grzegorz ;
Sowa, Mathew E. ;
Chen, Jing ;
Liang, Anthony ;
Hannon, Gregory J. ;
Sorger, Peter K. ;
Harper, J. Wade ;
Elledge, Stephen J. .
NATURE CELL BIOLOGY, 2007, 9 (05) :556-U136
[3]   Regulatory roles of natural antisense transcripts [J].
Faghihi, Mohammad Ali ;
Wahlestedt, Claes .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2009, 10 (09) :637-643
[4]   Constitutive kinase activation of the TEL-Syk fusion gene in myelodysplastic syndrome with t(9;12)(q22;p12) [J].
Kuno, Y ;
Abe, A ;
Emi, N ;
Iida, M ;
Yokozawa, T ;
Towatari, M ;
Tanimoto, M ;
Saito, H .
BLOOD, 2001, 97 (04) :1050-1055
[5]   Oncogenic transcription factors in the human acute leukemias [J].
Look, AT .
SCIENCE, 1997, 278 (5340) :1059-1064
[6]   Small RNAs in transcriptional gene silencing and genome defence [J].
Moazed, Danesh .
NATURE, 2009, 457 (7228) :413-420
[7]   Long Noncoding RNAs with Enhancer-like Function in Human Cells [J].
Orom, Ulf Andersson ;
Derrien, Thomas ;
Beringer, Malte ;
Gumireddy, Kiranmai ;
Gardini, Alessandro ;
Bussotti, Giovanni ;
Lai, Fan ;
Zytnicki, Matthias ;
Notredame, Cedric ;
Huang, Qihong ;
Guigo, Roderic ;
Shiekhattar, Ramin .
CELL, 2010, 143 (01) :46-58
[8]   A novel cryptic translocation t(12;17)(p13;p12-p13) in a secondary acute myeloid leukemia results in a fusion of the ETV6 gene and the antisense strand of the PERI gene [J].
Penas, EMM ;
Cools, J ;
Algenstaedt, P ;
Hinz, K ;
Seeger, D ;
Schafhausen, P ;
Schilling, G ;
Marynen, P ;
Hossfeld, DK ;
Dierlamm, J .
GENES CHROMOSOMES & CANCER, 2003, 37 (01) :79-83
[9]   TAO kinases mediate activation of p38 in response to DNA damage [J].
Raman, Malavika ;
Earnest, Svetlana ;
Zhang, Kai ;
Zhao, Yingming ;
Cobb, Melanie H. .
EMBO JOURNAL, 2007, 26 (08) :2005-2014
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