Photon upconverting nanoparticles for luminescent sensing of temperature

被引：209

作者：

Sedlmeier, Andreas ^{[1
]}

Achatz, Daniela E. ^{[1
]}

Fischer, Lorenz H. ^{[1
]}

Gorris, Hans H. ^{[1
]}

Wolfbeis, Otto S. ^{[1
]}

机构：

[1] Univ Regensburg, Inst Analyt Chem Chemo & Biosensors, D-93040 Regensburg, Germany

来源：

NANOSCALE | 2012年 / 4卷 / 22期

关键词：

UP-CONVERSION FLUORESCENCE; MICROFLUIDIC SYSTEMS; NANOCRYSTALS; THERMOMETRY; MICRODROPLETS; SENSITIVITY; EMISSION; TERBIUM; PROBES; SENSOR;

D O I：

10.1039/c2nr32314a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Photon upconverting nanoparticles convert near-infrared into visible light (anti-Stokes emission), which strongly reduces the background of autofluorescence and light scattering in biological materials. Hexagonal NaYF4 nanocrystals doped with Yb3+ as the sensitizer and Er3+/Ho3+/Tm3+ as the activator display at least two emission lines that respond differently to temperature changes. The ratio of the main emission line intensities enables a self-referenced optical readout of the temperature in the physiologically relevant range from 20 to 45 degrees C. Upconverting nanoparticles of the type NaYF4:Yb, Er covered by an inactive shell of NaYF4 are bright and allow for resolving temperature differences of less than 0.5 degrees C in the physiological range. The optical readout of this nanoparticle-based thermometer offers many options for imaging the two-dimensional distribution of temperature.

引用

页码：7090 / 7096

页数：7

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