Alkynyl halides in ruthenium(II)-catalyzed [2+2] cycloadditions of bicyclic alkenes

被引:57
作者
Allen, Anna [1 ]
Villeneuve, Karine [1 ]
Cockburn, Neil [1 ]
Fatila, Elisabeth [1 ]
Riddell, Nicole [1 ]
Tam, William [1 ]
机构
[1] Univ Guelph, Dept Chem, Guelph Waterloo Ctr Grad Work Chem & Biochem, Guelph, ON N1G 2W1, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
ruthenium; cycloaddition; bicyclic alkenes; alkynyl halides; homogeneous catalysis;
D O I
10.1002/ejoc.200800424
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Ru-catalyzed [2+2] cycloadditions between bicyclic alkenes and alkynyl halides were found to occur in moderate to good yields. The presence of the halide moiety greatly enhances the reactivity of the alkyne component in the cycloaddition and can be transformed into a variety of products that are difficult or impossible to obtain by direct cycloaddition. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008).
引用
收藏
页码:4178 / 4192
页数:15
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