Liquid chromatographic determination of inositol hexanicotinate in formulated preparations

被引：0

作者：

Nagarajan, M

Waszkuc, TW

Sun, JD

机构：

来源：

JOURNAL OF AOAC INTERNATIONAL | 1997年 / 80卷 / 04期

关键词：

D O I：

暂无

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A precise and selective liquid chromatographic procedure for determining inositol hexanicotinate (IHN) in formulated preparations was developed and validated, IHN was dissolved in dimethyl sulfoxide, diluted with acetonitrile, chromatographed on a Nova-Pak C-18 column with a mobile phase of water-methanol (40 + 60, v/v), and detected at 262 nm, The correlation coefficient of the calibration curve was 0.9995 over the range 0.05-0.15 mg/mL. Overall recovery of IHN was >97%. Coefficients of variation for intra- and interday precisions were <2%.

引用

页码：762 / 766

页数：5

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