Structural Neuroimaging in Aging and Alzheimer's Disease

被引：26

作者：

Vernooij, Meike W. ^{[1
,2
]}

Smits, Marion ^{[1
]}

机构：

[1] Erasmus MC, Dept Radiol, Univ Med Ctr, NL-3000 CA Rotterdam, Netherlands

[2] Erasmus MC, Dept Epidemiol, Univ Med Ctr, NL-3000 CA Rotterdam, Netherlands

来源：

NEUROIMAGING CLINICS OF NORTH AMERICA | 2012年 / 22卷 / 01期

关键词：

Dementia; Alzheimer's disease; Magnetic resonance (MR) imaging; Normal aging; Brain; Atrophy; Neuroimaging; POSTERIOR CORTICAL ATROPHY; VIRCHOW-ROBIN SPACES; WHITE-MATTER HYPERINTENSITIES; ENLARGED PERIVASCULAR SPACES; MILD COGNITIVE IMPAIRMENT; CREUTZFELDT-JAKOB-DISEASE; MAGNETIC-RESONANCE IMAGES; MEDIAL TEMPORAL-LOBE; SMALL VESSEL DISEASE; CEREBRAL MICROBLEEDS;

D O I：

10.1016/j.nic.2011.11.007

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The role of structural neuroimaging in the diagnosis of Alzheimer's disease (AD) is becoming increasingly important. As a consequence, a basic understanding of what are normal brain changes in aging is key to be able to recognize what is abnormal. The first part of this article discusses normal versus pathologic brain aging, focusing on qualitative and quantitative magnetic resonance (MR) imaging markers. In the second part, the role of MR imaging in the (differential) diagnosis of AD is reviewed.

引用

页码：33 / +

页数：25

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