Alzheimer's disease drug discovery targeted to the nonamyloidogenic path of APP mRNA translation linked to Alpha-secretase (ADAM-17) expression

被引：0
|
作者：
Rogers, Jack T. [1 ]
Cahill, Catherine M.
Cho, Hyun Hee
Moncaster, Juliet A. [2 ]
Goldstein, Lee E. [2 ]
Moir, Robert [3 ]
Xie, Zhongcong [3 ]
Huang, Xudong
机构：
[1] Massachusetts Gen Hosp, Dept Pf Psychiat Neurosci, Charlestown, MA 02129 USA
[2] BU, Sch Med, Charlestown, MA USA
[3] Massachusetts Gen Hosp, Genet & Aging Res Unit, Charlestown, MA USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 237卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
150-MEDI
引用
收藏
页数：1
相关论文
共 9 条
  • [1] Alpha-Secretase ADAM10 Regulation: Insights into Alzheimer's Disease Treatment
    Peron, Rafaela
    Vatanabe, Izabela Pereira
    Regina Manzine, Patricia
    Camins, Antoni
    Cominetti, Marcia Regina
    PHARMACEUTICALS, 2018, 11 (01)
  • [2] Alzheimer's disease drug discovery targeted to the APP mRNA 5′untranslated region
    Rogers, JT
    Randall, JD
    Eder, PS
    Huang, XD
    Bush, AI
    Tanzi, RE
    Venti, A
    Payton, SM
    Giordano, T
    Nagano, S
    Cahill, CM
    Moir, R
    Lahiri, DK
    Greig, N
    Sarang, SS
    Gullans, SR
    JOURNAL OF MOLECULAR NEUROSCIENCE, 2002, 19 (1-2) : 77 - 82
  • [3] Alzheimer’s disease drug discovery targeted to the APP mRNA 5′Untranslated region
    Jack T. Rogers
    Jeffrey D. Randall
    Paul S. Eder
    Xudong Huang
    Ashley I. Bush
    Rudolph E. Tanzi
    Amanda Venti
    Sandra M. Payton
    Tony Giordano
    Seiichi Nagano
    Catherine M. Cahill
    Robert Moir
    Debomoy K. Lahiri
    Nigel Greig
    Satinder Singh Sarang
    Steven R. Gullans
    Journal of Molecular Neuroscience, 2002, 19 : 77 - 82
  • [4] Alzheimer's disease drug discovery targeted to the APP mRNA 5′ untranslated region
    Rogers, J
    Payton, S
    Huang, XD
    Randall, J
    Sarang, S
    Gullans, S
    Giordano, T
    NEUROBIOLOGY OF AGING, 2002, 23 (01) : S79 - S79
  • [5] EHT 0202: a neuroprotective and procognitive alpha-secretase stimulator targeted towards Alzheimer's disease therapy
    Desire, L.
    Drouin, D.
    Sol, O.
    Lambeng, N.
    Schweighoffer, F.
    EUROPEAN JOURNAL OF NEUROLOGY, 2008, 15 : 37 - 37
  • [6] Alzheimer's disease drug discovery targeted to the APP MRNA 5′ untranslated region, a validated target
    Rogers, JT
    Payton, S
    Greig, NH
    Jensen, R
    Cuny, G
    Lahiri, DK
    Morse, LJ
    Tanzi, RE
    Westaway, D
    Bush, A
    Gullans, S
    Sarang, S
    Huang, XD
    NEUROBIOLOGY OF AGING, 2004, 25 : S589 - S589
  • [7] Drug discovery targeted to the Alzheimer’s APP mRNA 5′-untranslated regionThe action of paroxetine and dimercaptopropanol
    Sandra Payton
    Catherine M. Cahill
    Jeffrey D. Randall
    Steven R. Gullans
    Jack T. Rogers
    Journal of Molecular Neuroscience, 2003, 20 : 267 - 275
  • [8] Drug discovery targeted to the Alzheimer's APP mRNA 5′-untranslated region -: The action of paroxetine and dimercaptopropanol
    Payton, S
    Cahill, CM
    Randall, JD
    Gullans, SR
    Rogers, JT
    JOURNAL OF MOLECULAR NEUROSCIENCE, 2003, 20 (03) : 267 - 275
  • [9] Reduced microvascular expression of ADAM17 contributes to cognitive impairment in Alzheimer's disease model, APP/PS1 mice
    Tian, Yanna
    Buncha, Vadym
    Fopiano, Katie Anne
    Balogh, Marta
    Martinez, Carlos G.
    Lang, Liwei
    Bagi, Zsolt
    FASEB JOURNAL, 2022, 36
1