Two New Resveratrol Trimers with Antibacterial Activities from Seed Cake of Paeonia rockii

被引:16
作者
Liu, Pu [1 ,2 ]
Li, Xiao-Fang [1 ,2 ]
Gao, Jia-Yu [1 ,2 ]
Liu, Yi-qiong [1 ]
Hou, Xue-Wen [1 ]
Yin, Wei-Ping [1 ,2 ]
Deng, Rui-Xue [1 ,2 ]
机构
[1] Henan Univ Sci & Technol, Chem Engn & Pharmaceut Coll, Luoyang 471003, Peoples R China
[2] Res Ctr Wild Nat Resources FUNIU Mt, Luoyang 471003, Henan Province, Peoples R China
基金
中国国家自然科学基金;
关键词
seed cake; Paeonia rockii; resveratrol trimers; antibacterial activity;
D O I
10.1007/s10600-017-1909-3
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Bioactivity-guided fractionation of the EtOAc-soluble fraction of the total ethanolic extract resulted in the isolation and identification of two new resveratrol trimers, rockiol A (1) and rockiol B (2). The relative configurations of these compounds were elucidated mainly by comprehensive 1D and 2D NMR experiments. The two isolated compounds exhibited strong antibacterial activities against Gram-positive bacteria.
引用
收藏
页码:51 / 55
页数:5
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