Flavonoids from Pseudotsuga menziesii

被引：9

作者：

Krauze-Baranowska, Miroslawa ^{[1
]}

Sowinski, Pawel ^{[2
]}

Kawiak, Anna ^{[3
,4
,5
]}

Sparzak, Barbara ^{[5
]}

机构：

[1] Med Univ Gdansk, Dept Pharmacognosy, PL-80416 Gdansk, Poland

[2] Tech Univ, Fac Chem, NMR Lab, Gdansk, Poland

[3] Univ Gdansk, Intercollegiate Fac Biotechnol, Dept Biotechnol, PL-80822 Gdansk, Poland

[4] Med Univ Gdansk, PL-80822 Gdansk, Poland

[5] Med Univ Gdansk, Fac Hlth Sci, Subfac Nursing, Lab Human Physiol, PL-80210 Gdansk, Poland

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES | 2013年 / 68卷 / 3-4期

关键词：

Pseudotsuga menziesii; O-Acylated Flavonol Glycosides; beta-Truxinic Acid Derivatives; DOUGLAS-FIR; GLYCOSIDES; LEAVES; PROANTHOCYANIDINS; CONSTITUENTS; FRANCO; ESTERS; BARK; ACID; LEAF;

D O I：

10.5560/ZNC.2013.68c0087

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Four O-acylated flavonol glycosides, new in the plant kingdom, were isolated from the needles of Pseudotsuga menziesii. Their structures were established by 1D and 2D NMR and MS data as: daglesioside I [kaempferol 3-O-[2 '',5 ''-O-(4''',4(IV)-dihydroxy)-beta-truxinoyl]-alpha-L-arabinofuranoside] (1), daglesioside II [kaempferol 3-O-[2 '',5 ''-O-(4'''-hydroxy)-beta-truxinoyl]-alpha-L-arabinofuranoside] (2), daglesioside III [kaempferol 3-O-[2 '',5 ''-di-O-(E)-p-coumaroyl]-alpha-L-arabinofuranoside] (3), and daglesioside IV [kaempferol 3-O-[3 '',6 ''-di-O-(E)-cinnamoyl]-beta-D-glucopyranoside] (4). In addition, the known flavonoids (E)-tiliroside, (E)-ditiliroside, astragalin (kaempferol 3-O-beta-D-glucopyranoside), isorhamnetin, kaempferol, and quercetin were identified. The cytotoxic activity of compounds 1 and 3 was evaluated towards the HL-60, HeLa, and MDA-MB468 cell lines.

引用

页码：87 / 96

页数：10

共 29 条

[1] A new acylated flavonol triglycoside from Carrichtera annua
Abdel-Shafeek, KA
El-Messiry, MM
Shahat, AA
Apers, S
Pieters, L
Seif-El Nasr, MM
[J]. JOURNAL OF NATURAL PRODUCTS, 2000, 63 (06): : 845 - 847
[2] [Anonymous], 1999, HDB NATURAL FLAVONOI
[3] Dimeric tropane alkaloids from Erythroxylum moonii
Atta-Ur-Rahman
Khattak, KF
Nighat, F
Shabbir, M
Hemalal, KD
Tillekeratne, LM
[J]. PHYTOCHEMISTRY, 1998, 48 (02) : 377 - 383
[4] COMPARATIVE INVESTIGATION OF DOUGLAS-FIR HEADSPACE SAMPLES, ESSENTIAL OILS, AND EXTRACTS (NEEDLES AND TWIGS) USING GC-FID AND GC-FTIR-MS
BUCHBAUER, G
JIROVETZ, L
WASICKY, M
NIKIFOROV, A
[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1994, 42 (12) : 2852 - 2854
[5] PHENYLPROPANOID ESTERS FROM LAMIUM-ALBUM FLOWERS
BUDZIANOWSKI, J
SKRZYPCZAK, L
[J]. PHYTOCHEMISTRY, 1995, 38 (04) : 997 - 1001
[6] Flavonoid, iridoid, and lignan glycosides from Putoria calabrica
Çalis, I
Heilmann, J
Tasdemir, D
Linden, A
Ireland, CM
Sticher, O
[J]. JOURNAL OF NATURAL PRODUCTS, 2001, 64 (07): : 961 - 964
[7] Douglas-fir polyphenols and heartwood formation
Dellus, V
Mila, I
Scalbert, A
Menard, C
Michon, V
duPenhoat, CLMH
[J]. PHYTOCHEMISTRY, 1997, 45 (08) : 1573 - 1578
[8] STACHYSETIN, A DIAPIGENIN-7-GLUCOSIDE-P,P'-DIHYDROXYTRUXINATE FROM STACHYS AEGYPTIACA
ELANSARI, MA
NAWWAR, MA
SALEH, NAM
[J]. PHYTOCHEMISTRY, 1995, 40 (05) : 1543 - 1548
[9] FOO LY, 1992, PHYTOCHEMISTRY, V31, P1444, DOI 10.1016/0031-9422(92)80317-8
[10] FOO LY, 1989, PHYTOCHEMISTRY, V28, P1237, DOI 10.1016/0031-9422(89)80217-1

← 1 2 3 →