Flavonoids from Pseudotsuga menziesii

被引：10

作者：

Krauze-Baranowska, Miroslawa ^{[1
]}

Sowinski, Pawel ^{[2
]}

Kawiak, Anna ^{[3
,4
,5
]}

Sparzak, Barbara ^{[5
]}

机构：

[1] Med Univ Gdansk, Dept Pharmacognosy, PL-80416 Gdansk, Poland

[2] Tech Univ, Fac Chem, NMR Lab, Gdansk, Poland

[3] Univ Gdansk, Intercollegiate Fac Biotechnol, Dept Biotechnol, PL-80822 Gdansk, Poland

[4] Med Univ Gdansk, PL-80822 Gdansk, Poland

[5] Med Univ Gdansk, Fac Hlth Sci, Subfac Nursing, Lab Human Physiol, PL-80210 Gdansk, Poland

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES | 2013年 / 68卷 / 3-4期

关键词：

Pseudotsuga menziesii; O-Acylated Flavonol Glycosides; beta-Truxinic Acid Derivatives; DOUGLAS-FIR; GLYCOSIDES; LEAVES; PROANTHOCYANIDINS; CONSTITUENTS; FRANCO; ESTERS; BARK; ACID; LEAF;

D O I：

10.5560/ZNC.2013.68c0087

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Four O-acylated flavonol glycosides, new in the plant kingdom, were isolated from the needles of Pseudotsuga menziesii. Their structures were established by 1D and 2D NMR and MS data as: daglesioside I [kaempferol 3-O-[2 '',5 ''-O-(4''',4(IV)-dihydroxy)-beta-truxinoyl]-alpha-L-arabinofuranoside] (1), daglesioside II [kaempferol 3-O-[2 '',5 ''-O-(4'''-hydroxy)-beta-truxinoyl]-alpha-L-arabinofuranoside] (2), daglesioside III [kaempferol 3-O-[2 '',5 ''-di-O-(E)-p-coumaroyl]-alpha-L-arabinofuranoside] (3), and daglesioside IV [kaempferol 3-O-[3 '',6 ''-di-O-(E)-cinnamoyl]-beta-D-glucopyranoside] (4). In addition, the known flavonoids (E)-tiliroside, (E)-ditiliroside, astragalin (kaempferol 3-O-beta-D-glucopyranoside), isorhamnetin, kaempferol, and quercetin were identified. The cytotoxic activity of compounds 1 and 3 was evaluated towards the HL-60, HeLa, and MDA-MB468 cell lines.

引用

页码：87 / 96

页数：10

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