Sesquiterpenes from the marine algicolous fungus Drechslera sp.

被引:10
作者
Abdel-Lateff, Ahmed [1 ]
Okino, Tatsufumi [2 ]
Alarif, Walied M. [3 ]
Al-Lihaibi, Sultan S. [3 ]
机构
[1] King Abdulaziz Univ, Deptartment Nat Prod & Alternat Med, Fac Pharm, Jeddah 21589, Saudi Arabia
[2] Hokkaido Univ, Fac Environm Earth Sci, Sapporo, Hokkaido 0600810, Japan
[3] King Abdulaziz Univ, Marine Chem Dept, Fac Marine Sci, Jeddah 21589, Saudi Arabia
关键词
Marine microorganism; Fungi; Sesquiterpenes; Drechslera sp; SORBICILLIN DERIVATIVES; HELMINTHOSPOROL; METABOLITES;
D O I
10.1016/j.jscs.2011.03.002
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A marine fungal isolate, identified as Drechslera sp., was mass cultivated and found to produce a new naturally occurring seco-sativene type sesquiterpene helminthosporic acid (1) and three known sesquiterpenes, helminthosporol (2), drechslerine A (3) and (+) secolongifolene-diol (4). The structures of all compounds were determined by interpretation of their spectroscopic data 1D (H-1 and C-13), 2D (COSY, DQF, NOE, HSQC and HMBC) NMR, MS, UV and IR analyses. All compounds have been tested toward antioxidants, antimicrobial and antifouling effects. (c) 2011 King Saud University. Production and hosting by Elsevier B.V. All rights reserved.
引用
收藏
页码:161 / 165
页数:5
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