Salmonella enterica serovar Typhi osteomyelitis in a young adult with sickle cell and thalassemia traits: A possible association

被引：4
作者：
Stephanie, Stephanie [1 ]
Schmalzle, Sarah A. [1 ,2 ,3 ]
机构：
[1] Univ Maryland, Med Ctr, Midtown Campus,827 Linden Ave, Baltimore, MD 21201 USA
[2] Univ Maryland, Sch Med, Inst Human Virol, 725 West Lombard St, Baltimore, MD 21201 USA
[3] Univ Maryland, Sch Med, Div Infect Dis, 22 S Greene St, Baltimore, MD 21201 USA
来源：
IDCASES | 2019年 / 15卷
关键词：
Salmonella; Typhoid fever; Osteomyelitis; Sickle cell; Thalassemia; Hemoglobinopathy; ABSCESS; DEATH;
D O I：
10.1016/j.idcr.2018.e00478
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Salmonella osteomyelitis is known to occur in immunocompromised and sickle cell disease patients. It rarely occurs in other hosts. We present a case of chronic femoral osteomyelitis due to S. enterica serovar Typhi seen in a Maryland resident. Potential risk factors included traveling to an endemic area as well as a newly diagnosed sickle cell trait and thalassemia trait. It is postulated that less severe hemoglobinopathies may also contribute to an elevated risk of Salmonella osteomyelitis. (C) 2018 The Authors. Published by Elsevier Ltd.
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