Angular compounding by full-channel B-scan modulation encoding for optical coherence tomography speckle reduction

被引:12
作者
Li, Pei [1 ]
Zhou, Liping [1 ]
Ni, Yang [1 ]
Ding, Zhihua [1 ]
Li, Peng [1 ]
机构
[1] Zhejiang Univ, Coll Opt Sci & Engn, State Key Lab Modern Opt Instrumentat, Hangzhou 310027, Zhejiang, Peoples R China
基金
中国国家自然科学基金;
关键词
optical coherence tomography; medical and biological imaging; speckle reduction; angular compounding; AMPLITUDE-DECORRELATION ANGIOGRAPHY; SPECTRUM;
D O I
10.1117/1.JBO.21.8.086014
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We describe an angular compounding method by full-channel B-scan modulation encoding for speckle reduction in optical coherence tomography. The complex-valued spectral interferogram (SI) is reconstructed by removing one of the conjugate terms in the depth space. Fourier transform of the complex SI along the lateral direction enables a full-channel (with both negative and positive Fourier space) for B-scan modulation in the spatial frequency (v) domain. A full-size probe beam, determined by the scanning mirror size, is centered on the mirror pivot, which allows the negative and positive half-channels working in parallel. Compared with the existing method, where only a half-channel (negative or positive) works alone, the proposed full-channel method offers more than twice the performance in speckle reduction. The feasibility of the proposed full-space approach is validated through both the phantom and in vivo human thumbnail experiments. (C) 2016 Society of Photo-Optical Instrumentation Engineers (SPIE)
引用
收藏
页数:6
相关论文
共 19 条
[11]   Speckle reduction in optical coherence tomography by "path length encoded" angular compounding [J].
Iftimia, N ;
Bouma, BE ;
Tearney, GJ .
JOURNAL OF BIOMEDICAL OPTICS, 2003, 8 (02) :260-263
[12]   Split-spectrum amplitude-decorrelation angiography with optical coherence tomography [J].
Jia, Yali ;
Tan, Ou ;
Tokayer, Jason ;
Potsaid, Benjamin ;
Wang, Yimin ;
Liu, Jonathan J. ;
Kraus, Martin F. ;
Subhash, Hrebesh ;
Fujimoto, James G. ;
Hornegger, Joachim ;
Huang, David .
OPTICS EXPRESS, 2012, 20 (04) :4710-4725
[13]   Speckle reduction in optical coherence tomography by strain compounding [J].
Kennedy, Brendan F. ;
Hillman, Timothy R. ;
Curatolo, Andrea ;
Sampson, David D. .
OPTICS LETTERS, 2010, 35 (14) :2445-2447
[14]   Single-shot angular compounded optical coherence tomography angiography by splitting full-space B-scan modulation spectrum for flow contrast enhancement [J].
Li, Pei ;
Cheng, Yuxuan ;
Zhou, Liping ;
Pan, Cong ;
Ding, Zhihua ;
Li, Peng .
OPTICS LETTERS, 2016, 41 (05) :1058-1061
[15]   Assessment of Full-Eye Response to Osmotic Stress in Mouse Model In Vivo Using Optical Coherence Tomography [J].
Ni, Yang ;
Xu, Baisheng ;
Wu, Lan ;
Du, Chixin ;
Jiang, Bo ;
Ding, Zhihua ;
Li, Peng .
JOURNAL OF OPHTHALMOLOGY, 2015, 2015
[16]   Speckle reduction in optical coherence tomography by frequency compounding [J].
Pircher, M ;
Götzinger, E ;
Leitgeb, R ;
Fercher, AF ;
Hitzenberger, CK .
JOURNAL OF BIOMEDICAL OPTICS, 2003, 8 (03) :565-569
[17]   Speckle in optical coherence tomography [J].
Schmitt, JM ;
Xiang, SH ;
Yung, KM .
JOURNAL OF BIOMEDICAL OPTICS, 1999, 4 (01) :95-105
[18]   Assessment of Tear Meniscus with Optical Coherence Tomography in Thyroid-Associated Ophtalmopathy [J].
Sizmaz, Selcuk ;
Altan-Yaycioglu, Rana ;
Bakiner, Okan Sefa ;
Bozkirli, Emre ;
Coban-Karatas, Muge ;
Ulas, Burak .
CURRENT EYE RESEARCH, 2014, 39 (04) :323-328
[19]   Speckle reduction in optical coherence tomography using angular compounding by B-scan Doppler-shift encoding [J].
Wang, Hui ;
Rollins, Andrew M. .
JOURNAL OF BIOMEDICAL OPTICS, 2009, 14 (03)