Angular compounding by full-channel B-scan modulation encoding for optical coherence tomography speckle reduction

被引:12
作者
Li, Pei [1 ]
Zhou, Liping [1 ]
Ni, Yang [1 ]
Ding, Zhihua [1 ]
Li, Peng [1 ]
机构
[1] Zhejiang Univ, Coll Opt Sci & Engn, State Key Lab Modern Opt Instrumentat, Hangzhou 310027, Zhejiang, Peoples R China
基金
中国国家自然科学基金;
关键词
optical coherence tomography; medical and biological imaging; speckle reduction; angular compounding; AMPLITUDE-DECORRELATION ANGIOGRAPHY; SPECTRUM;
D O I
10.1117/1.JBO.21.8.086014
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We describe an angular compounding method by full-channel B-scan modulation encoding for speckle reduction in optical coherence tomography. The complex-valued spectral interferogram (SI) is reconstructed by removing one of the conjugate terms in the depth space. Fourier transform of the complex SI along the lateral direction enables a full-channel (with both negative and positive Fourier space) for B-scan modulation in the spatial frequency (v) domain. A full-size probe beam, determined by the scanning mirror size, is centered on the mirror pivot, which allows the negative and positive half-channels working in parallel. Compared with the existing method, where only a half-channel (negative or positive) works alone, the proposed full-channel method offers more than twice the performance in speckle reduction. The feasibility of the proposed full-space approach is validated through both the phantom and in vivo human thumbnail experiments. (C) 2016 Society of Photo-Optical Instrumentation Engineers (SPIE)
引用
收藏
页数:6
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