Outbreak of hand, foot, and mouth disease caused by coxsackievirus A6 in a Juku in Fengtai District, Beijing, China, 2015

被引：14

作者：

Li, Jin-Song ^{[1
]}

Dong, Xiao-Gen ^{[2
]}

Qin, Meng ^{[2
]}

Feng, Hui-Ru ^{[2
]}

Yang, Jun-Yong ^{[2
]}

Li, Ruo-Xi ^{[2
]}

Zhang, Jian-Jun ^{[2
]}

Zheng, Li-Shu ^{[1
]}

机构：

[1] China CDC, Natl Inst Viral Dis Control & Prevent, Key Lab Med Virol, Minist Hlth, 100 Ying Xin St, Beijing 100052, Peoples R China

[2] Fengtai Dist Ctr Dis Control & Prevent Beijing, 3 Xi An St, Beijing 100071, Peoples R China

来源：

SPRINGERPLUS | 2016年 / 5卷

关键词：

Coxsackievirus A6; HFMD; Outbreak; ATYPICAL HAND;

D O I：

10.1186/s40064-016-3307-x

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

An outbreak of hand, foot, and mouth disease (HFMD) that occurred in a Juku in Fengtai District, Beijing, China, in 2015 was monitored by the China Information System for Disease Control and Prevention. Epidemiological investigation showed that 11 cases occurred from two classes in the preschool art training department in the Juku. Coxsackievirus A6 (CV-A6) was identified as the causative pathogen of the outbreak via sequences analysis of products of real-time reverse-transcription polymerase chain reaction (RT-PCR) and nested RT-PCR. Phylogenetic analysis showed that CV-A6 strains isolated in this study clustered with epidemic strains isolated in China since 2013. The outbreak ended quickly with effective measures. This event indicates that continuous surveillance of HFMD etiological agents other than enterovirus 71 and coxsackievirus A16 is necessary.

引用

页数：4

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