Direct ionization methods in mass spectrometry: An overview

被引:102
作者
Klampfl, Christian W. [1 ]
Himmelsbach, Markus [1 ]
机构
[1] Johannes Kepler Univ Linz, Inst Analyt Chem, A-4040 Linz, Austria
关键词
Ambient ionization; Ambient ionization mass spectrometry; Direct electrospray probe; Direct ionization mass spectrometry; Paper spray; Probe electrospray ionization; Wooden tip electrospray ionization; Leaf spray; Thin layer chromatography spray; PROBE ELECTROSPRAY-IONIZATION; PAPER SPRAY IONIZATION; SOLID-PHASE MICROEXTRACTION; THIN-LAYER-CHROMATOGRAPHY; IN-SITU ANALYSIS; QUANTITATIVE-ANALYSIS; CANCER DIAGNOSTICS; RAPID DETECTION; BIOLOGICAL TISSUE; IDENTIFICATION;
D O I
10.1016/j.aca.2015.07.012
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Within this paper a sub-group of ambient ionization mass spectrometry namely direct ionization mass spectrometry techniques are reviewed. They are characterized by the generation of an electrospray directly from the sample investigated. Prominent representatives include paper spray mass spectrometry, tissue spray mass spectrometry, probe electrospray ionization or thin-layer chromatography mass spectrometry. Applications of all major direct ionization techniques within different fields such as biomedical analysis, analysis of natural products, analysis of technical products and food analysis, just to name a few, are discussed and relevant parameters are listed in five Tables. (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码:44 / 59
页数:16
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