Preparation and self-assembly of amphiphilic polymer with aggregation-induced emission characteristics

被引:47
|
作者
Qin AnJun [1 ]
Zhang Ya [2 ]
Han Ning [3 ]
Mei Ju [1 ]
Sun JingZhi [1 ]
Fan WeiMin [3 ]
Tang Ben Zhong [1 ,4 ]
机构
[1] Zhejiang Univ, Dept Polymer Sci & Engn, MOE Key Lab Macromol Synth & Functionalizat, Hangzhou 310027, Zhejiang, Peoples R China
[2] Zhejiang Univ, Dept Chem, Hangzhou 310027, Zhejiang, Peoples R China
[3] Zhejiang Univ, Coll Med, Hangzhou 310027, Zhejiang, Peoples R China
[4] Hong Kong Univ Sci & Technol, State Key Lab Mol Neurosci, Inst Mol Funct Mat, Dept Chem, Kowloon, Hong Kong, Peoples R China
基金
中国国家自然科学基金;
关键词
amphiphilic polymer; aggregation-induced emission; tetraphenylethene; self-assembly; cell imaging;
D O I
10.1007/s11426-012-4528-7
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An amphiphilic polymer bearing tetraphenylethene (TPE) moiety was synthesized by convenient reactions. The polymer exhibits unique aggregation-induced emission (AIE) characteristics and can self-assemble to size-tunable particles in DMF/water mixtures. The polymer nanoparticles can be used for cell imaging, which provides a potential stable fluorescent tool to monitor the distribution of drugs and bioconjugates in living cells.
引用
收藏
页码:772 / 778
页数:7
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