Recent developments in biomaterials for long-bone segmental defect reconstruction: A narrative overview

被引：83

作者：

Zhang, Meng ^{[1
]}

Matinlinna, Jukka P. ^{[2
]}

Tsoi, James K. H. ^{[2
]}

Liu, Wenlong ^{[1
]}

Cui, Xu ^{[1
]}

Lu, William W. ^{[1
,3
]}

Pan, Haobo ^{[1
]}

机构：

[1] Chinese Acad Sci, Res Ctr Human Tissues & Organs Degenerat, Inst Biomed & Biotechnol, Shenzhen Inst Adv Technol, 1068 Xueyuan Ave, Shenzhen 518055, Peoples R China

[2] Univ Hong Kong, Appl Oral Sci, Fac Dent, Sai Ying Pun, 34 Hosp Rd, Hong Kong, Peoples R China

[3] Univ Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, 21 Sassoon Rd, Hong Kong, Peoples R China

来源：

JOURNAL OF ORTHOPAEDIC TRANSLATION | 2020年 / 22卷

基金：

中国国家自然科学基金;

关键词：

Allograft; Artificial material; Autograft; Biomaterial; Long-bone segmental defect reconstruction; Tissue engineering; VASCULARIZED FIBULAR GRAFT; STEM-CELLS PROMOTE; COMPOSITE SCAFFOLDS; ONCOLOGIC RECONSTRUCTION; MORPHOGENETIC PROTEIN-2; REPAIR; ALLOGRAFT; ANGIOGENESIS; MANAGEMENT; NONUNION;

D O I：

10.1016/j.jot.2019.09.005

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Reconstruction of long-bone segmental defects (LBSDs) has been one of the biggest challenges in orthopaedics. Biomaterials for the reconstruction are required to be strong, osteoinductive, osteoconductive, and allowing for fast angiogenesis, without causing any immune rejection or disease transmission. There are four main types of biomaterials including autograft, allograft, artificial material, and tissue-engineered bone. Remarkable progress has been made in LBSD reconstruction biomaterials in the last ten years. The translational potential of this article: Our aim is to summarize recent developments in the divided four biomaterials utilized in the LBSD reconstruction to provide the clinicians with new information and comprehension from the biomaterial point of view.

引用

页码：26 / 33

页数：8

共 75 条

[1]

Akram M, 2014, J PAK MED ASSOC, V64, pS154

[2]

[Anonymous], [No title captured]

[3]

[Anonymous], [No title captured]

[4]

[Anonymous], [No title captured]