A new flavanocoumarin from the root of Flemingia philippinensis

被引：12

作者：

Fu, Manqin ^{[1
,2
]}

Deng, Dun ^{[3
]}

Huang, Riming ^{[2
]}

Zhang, Nenling ^{[2
]}

Su, Zhiwei ^{[2
]}

Qiu, Samuel X. ^{[2
]}

机构：

[1] Guangdong Acad Agr Sci, Guangdong Open Access Lab Agr Prod Proc, Sericulture & Farm Produce Proc Res Inst, Guangzhou 510610, Guangdong, Peoples R China

[2] Chinese Acad Sci, South China Bot Garden, Key Lab Plant Resources Conservat & Sustainable U, Guangzhou 510650, Guangdong, Peoples R China

[3] Anhui Sci & Technol Univ, Coll Life Sci, Fengyang 233100, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2013年 / 27卷 / 14期

基金：

中国国家自然科学基金;

关键词：

Leguminosae; Flemingia philippinensis; flavanocoumarin; CIRCULAR-DICHROISM; ISOFLAVONES;

D O I：

10.1080/14786419.2012.724414

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

One new flavanocoumarin, flemicoumarin A (1) was isolated from the EtOAc-soluble partition of the root of Flemingia philippinensis, along with three known compounds, namely 4,2-epoxy-4,5-dihydroxy-7,5-dimethoxy-3-phenylcoumarin (2), kaempferol 6-C-glucoside (3) and dracocephaloside (4). The structure of compound 1 was elucidated on the basis of its 1D, 2D NMR, CD and MS data. The structures of the known compounds were identified by comparison of their spectroscopic data with those reported in the literature. Compounds 1-4 exhibited inactivity against MCF-7, A549 and Hep-G2 human cancer cell lines invitro by MTT colorimetric assay.

引用

页码：1237 / 1241

页数：5

共 16 条

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