Pd-catalyzed C3-selective arylation of pyridines with phenyl tosylates

被引：38

作者：

Dai, Fenglin ^{[1
]}

Gui, Qingwen ^{[1
]}

Liu, Jidan ^{[1
]}

Yang, Zhiyong ^{[1
]}

Chen, Xiang ^{[1
]}

Guo, Ruqing ^{[1
]}

Tan, Ze ^{[1
]}

机构：

[1] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Coll Chem & Chem Engn, Changsha 410082, Hunan, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 41期

基金：

美国国家科学基金会;

关键词：

C-H ARYLATION; ELECTRON-DEFICIENT POLYFLUOROARENES; ARYL TOSYLATES; SUZUKI-MIYAURA; BOND ACTIVATION; ARENES; FUNCTIONALIZATION; OLEFINATION; HALIDES; REGIOSELECTIVITY;

D O I：

10.1039/c3cc41066h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have discovered that phenyl tosylates can be used to arylate pyridines at the C3-position using a Pd(OAc)(2)-1,10-phenanthroline catalyst system. We also discovered that the reaction of 4-methylpyridine with naphthyl tosylates occurred on the methyl group instead of at the C3-position.

引用

页码：4634 / 4636

页数：3

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