Heterobilharziasis should be suspected in dogs with chronic diarrhea and weight loss that frequent areas where raccoons and lymnaeid snails are prevalent. Heterobilharziasis may be treated successfully with high doses of praziquantel, Use of saline solution sedimentation is essential for the detection of ova and miracidia in feces, Diagnosis of suspected infections in which ova are not evident in feces should be attempted by use of an ELISA for circulating fluke antigens in sera.