Therapeutic dosages of raloxifene do not modify myeloperoxidase and F2α-isoprostane levels in postmenopausal women

被引:4
作者
Oviedo, PJ
Hermenegildo, C
Tarín, JJ
Cano, A
机构
[1] Univ Valencia, Fac Med & Dent, Dept Pediat Obstet & Gynaecol, E-46010 Valencia, Spain
[2] Univ Valencia, Hosp Clin, Res Unit, Valencia, Spain
[3] Univ Valencia, Dept Physiol, Valencia, Spain
[4] Univ Valencia, Dept Funct Biol 7 Phys Anthropol, Valencia, Spain
关键词
D O I
10.1016/j.fertnstert.2005.05.072
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
We investigated the effect of a therapeutic dose of raloxifene on the plasma levels of myeloperoxidase and F-2 alpha-isoprostanes, two markers of oxidative stress recently described as reliable indicators of coronary heart disease. Contrary to changes described in the literature for estrogens (E), raloxifene did not modify the levels of either myeloproxidase or F-2 alpha-isoprostanes after 3 or 6 months of treatment.
引用
收藏
页码:1789 / 1792
页数:4
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