Th1 Cell Induction in Lymph Nodes According to a Red-Blue Chemokine Map

被引:11
作者
Matloubian, Mehrdad [1 ,2 ]
Cyster, Jason G. [3 ,4 ]
机构
[1] Univ Calif San Francisco, Dept Med, Div Rheumatol, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Rosalind Russell Med Res Ctr Arthrit, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USA
[4] Univ Calif San Francisco, Howard Hughes Med Inst, San Francisco, CA 94143 USA
关键词
RECEPTOR CXCR3; T-CELLS; GENERATION; EFFECTOR;
D O I
10.1016/j.immuni.2012.11.007
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Lymph nodes are compartmentalized organs but whether this feature has a role in T cell differentiation has been unclear. In this issue, Groom et al. (2012) reveal that spatially separated expression of two CXCR3 ligands guides Th1 cell development.
引用
收藏
页码:954 / 956
页数:3
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