Relationship of type of work with health-related quality of life

To examine the relation of work type with health-related quality of life (HRQoL) in healthy workers. We cross-sectionally examined 4427 (3605 men and 822 women) healthy workers in Japan, aged 19-69 years. We assessed HRQoL based on scores for five scales of the SF-36. Multiple regression was applied to examine the relation of work type (nighttime, shift, day to night, and daytime) with the five HRQoL norm-based scores, lower scores of which indicate poorer health status, adjusted for confounding factors, including sleeping duration. Shiftwork was inversely related to role physical [regression estimate (beta) = -2.12, 95 % confidence intervals (CI) -2.94, -1.30, P < 0.001], general health (beta = -1.37, 95 % CI -2.01, -0.72, P < 0.001), role emotional (beta = -1.24, 95% CI -1.98, -0.50, P < 0.001), and mental health (beta = -1.31, 95% CI -2.01, -0.63, P < 0.001) independent of confounding factors, but not to vitality. Day-to-nighttime work was inversely related to all the five HRQoL subscales (Ps 0.012 to < 0.001). Shiftwork was significantly inversely related to four out of the five HRQoL, except for vitality, and day-to-nighttime work was significantly inversely related to all five HRQoL, independent of demographic and lifestyle factors.