Cephalosporin resistant Escherichia coli from cancer patients in Cairo, Egypt

被引：9

作者：

Abdelaziz, Mohammed O. ^{[1
]}

Bonura, Celestino ^{[2
]}

Aleo, Aurora ^{[2
]}

Fasciana, Teresa ^{[2
]}

Cala, Cinzia ^{[2
]}

Mammina, Caterina ^{[2
]}

机构：

[1] Helwan Univ, Fac Pharm, Dept Microbiol & Immunol, Cairo 11795, Egypt

[2] Univ Palermo, Dept Sci Hlth Promot & Mother Child Care G DAless, I-90127 Palermo, Italy

来源：

MICROBIOLOGY AND IMMUNOLOGY | 2013年 / 57卷 / 05期

关键词：

cancer patients; CTX-M-15; Escherichia coli; multidrug resistance; BETA-LACTAMASES;

D O I：

10.1111/1348-0421.12046

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Cephalosporin-resistant Escherichia coli has been increasingly reported worldwide. In this study, 32 cephalosporin resistant E. coli isolates identified from cancer patients in Cairo, Egypt in 20092010 were analyzed. Twenty-three were of phylogenetic group D, seven A and one each B1 and B2. By rep-PCR 15 phylogroup D isolates were grouped in four clusters, one with sequence type (ST) 405 and three ST68. Seventeen isolates showed single patterns. blaCTX-M-15 and aac(6')-Ib-cr were the most common resistance determinants. blaOXA-48 and blaVIM were also detected. Multidrug resistant E. coli seriously affects healthcare, especially in immunocompromised hosts, such as cancer patients.

引用

页码：391 / 395

页数：5

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