Synthesis of Nitrogen- and Chlorine-Doped Graphene Quantum Dots for Cancer Cell Imaging

被引:19
|
作者
Nafiujjaman, Md [1 ]
Joon, Hwang [2 ]
Kwak, Kwang Soo [3 ]
Lee, Yong-kyu [1 ,3 ]
机构
[1] Korea Natl Univ Transportat, Dept Green Bioengn, Chungju 380702, South Korea
[2] Korea Natl Univ Transportat, Dept Aeronaut & Mech Design Engn, Chungju 380702, South Korea
[3] Korea Natl Univ Transportat, Dept Chem & Biol Engn, Chungju 380702, South Korea
关键词
Graphene Quantum Dots; Fructose; In Vitro; High Quantum Yield; Cell Imaging; CARBON DOTS; IN-VITRO; NANOPARTICLES; PHOTOLUMINESCENCE; NANOMATERIALS; FLUORESCENCE; FABRICATION; ACID;
D O I
10.1166/jnn.2018.15242
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this study, we synthesized high quantum yield nitrogen and chlorine-doped graphene quantum dots (Cl-GQDs-N) for cancer cell imaging using simple and high production yield hydrothermal method from low-cost fructose. Prepared Cl-GQDs-N are about 30 nm in diameter and these Cl-GQDs-N display powerful blue color photoluminescence under the 365 nm UV lamp. We have further investigated their optical performances under various conditions. In vitro study shows no toxicity effect in normal and cancer cells treated with Cl-GQDs-N. Finally, we believe that our synthesized Cl-GQDs-N will bring more application opportunities in the field of bioimaging, optoelectronics and beyond.
引用
收藏
页码:3793 / 3799
页数:7
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