Variation of Ursolic Acid Content in Eight Ocimum Species from Northeastern Brazil

被引:92
作者
Silva, M. Goretti V. [1 ]
Vieira, Icaro G. P. [2 ,3 ]
Mendes, Francisca N. P. [3 ]
Albuquerque, Irineu. L. [4 ]
dos Santos, Rogerio N. [1 ]
Silva, Fabio O. [1 ]
Morais, Selene M. [2 ]
机构
[1] Univ Fed Ceara, Dept Quim Analit & Fisicoquim, Dept Quim Organ & Inorgan, BR-60455970 Fortaleza, Ceara, Brazil
[2] Univ Estadual Ceara, Lab Quim Prod Nat, BR-60740000 Fortaleza, Ceara, Brazil
[3] Parque Desenvolvimento Tecnol PADETEC, BR-60455970 Fortaleza, Ceara, Brazil
[4] Univ Fortaleza, BR-60811905 Fortaleza, Ceara, Brazil
来源
MOLECULES | 2008年 / 13卷 / 10期
关键词
Labiatae; Ursolic acid; Ocimum; HPLC;
D O I
10.3390/molecules13102482
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Ursolic acid is a very important compound due to its biological potential as an anti-inflammatory, trypanocidal, antirheumatic, antiviral, antioxidant and antitumoral agent. This study presents the HPLC analysis of ursolic acid (UA) content in eight different Ocimum species: O. americanum L., O. basilicum L, O. basilicum var purpurascens Benth, O. basilicum var. minimum L, O. gratissimum L, O. micranthum Willd, O. selloi Benth. and O. tenuiflorum L. grown in Northeastern Brazil. In these Ocimum species, UA was detected in different yields, with O. tenuiflorum showing the highest content (2.02%). This yield is very significant when compared with other sources of UA.
引用
收藏
页码:2482 / 2487
页数:6
相关论文
共 15 条
  • [1] Chemistry of the genus Plectranthus
    Abdel-Mogib, M
    Albar, HA
    Batterjee, SM
    [J]. MOLECULES, 2002, 7 (02) : 271 - 301
  • [2] Ursolic acid as a trypanocidal constituent in rosemary
    Abe, F
    Yamauchi, T
    Nagao, T
    Kinjo, J
    Okabe, H
    Higo, H
    Akahane, H
    [J]. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2002, 25 (11) : 1485 - 1487
  • [3] Alves JS, 2000, MAGN RESON CHEM, V38, P201, DOI 10.1002/(SICI)1097-458X(200003)38:3<201::AID-MRC622>3.3.CO
  • [4] 2-S
  • [5] Anandjiwala S, 2006, J AOAC INT, V89, P1467
  • [6] High-performance liquid chromatographic analysis of bioactive triterpenes in Perilla frutescens
    Chen, JH
    Xia, ZH
    Tan, RX
    [J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2003, 32 (06) : 1175 - 1179
  • [7] Antiviral activities of extracts and selected pure constituents of Ocimum basilicum
    Chiang, LC
    Ng, LT
    Cheng, PW
    Chiang, W
    Lin, CC
    [J]. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2005, 32 (10): : 811 - 816
  • [8] Harmand PO, 2003, INT J ONCOL, V23, P105
  • [9] HUANG MT, 1994, CANCER RES, V54, P701
  • [10] Oleanolic acid and ursolic acid: Research perspectives
    Liu, H
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 2005, 100 (1-2) : 92 - 94