Persistent viremia and urine shedding of tick-borne encephalitis virus in an infected immunosuppressed patient from a new epidemic cluster in North-Eastern Italy

被引：30

作者：

Caracciolo, Ilaria ^{[1
]}

Bassetti, Matteo ^{[2
]}

Paladini, Giorgio ^{[3
]}

Luzzati, Roberto ^{[4
]}

Santon, Daniela ^{[1
]}

Merelli, Maria ^{[2
]}

De Sabbata, Giovanni ^{[3
]}

Carletti, Tea ^{[5
]}

Marcello, Alessandro ^{[6
]}

D'Agaro, Pierlanfranco ^{[1
,5
]}

机构：

[1] Univ Trieste, Dept Med Surg & Hlth Sci, Trieste, Italy

[2] Santa Maria Misericordia Univ Hosp, Infect Dis Clin, Udine, Italy

[3] Univ Hosp, Dept Oncol, Hematol Unit, Trieste, Italy

[4] Univ Hosp, Infect Dis Unit, Trieste, Italy

[5] IRCCS Burlo Garofolo, Inst Maternal & Child Hlth, Trieste, Italy

[6] ICGEB, Mol Virol Lab, Trieste, Italy

来源：

JOURNAL OF CLINICAL VIROLOGY | 2015年 / 69卷

关键词：

Tick-borne encephalitis; TBEV; Persistent infection; Immuno-compromized host; Real-time PCR; Virus isolation; Sequencing; Friuli-Venezia Giulia region; Trieste; Italy; IXODES-RICINUS;

D O I：

10.1016/j.jcv.2015.05.019

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A persistent tick-borne encephalitis virus infection in an immune-suppressed patient is presented. Such an unusual clinical case offers the unique chance of detecting persistent viremia associated to the erythrocyte fraction and shedding of the virus in the urine for more than six weeks. The infection occurred in a new area of the Friuli Venezia-Giulia region (North Eastern Italy) where two additional cases are also being reported. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：48 / 51

页数：4

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