Organocatalytic deprotonative functionalization of C(sp2)-H and C(sp3)-H bonds using in situ generated onium amide bases

被引：35

作者：

Inamoto, Kiyofumi ^{[1
]}

Okawa, Hitomi ^{[1
]}

Taneda, Hiroshi ^{[1
]}

Sato, Maomi ^{[1
]}

Hirono, Yutaro ^{[1
]}

Yonemoto, Misato ^{[1
]}

Kikkawa, Shoko ^{[1
]}

Kondo, Yoshinori ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Pharmaceut Sci, Aoba Ku, Sendai, Miyagi 9808578, Japan

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 78期

基金：

日本学术振兴会;

关键词：

C-H BONDS; DIRECTED METALATION; NUCLEOPHILIC TRIFLUOROMETHYLATION; CHEMOSELECTIVE BASE; DIAZINES PYRIDINES; CARBONYL-COMPOUNDS; N-BUTYLLITHIUM; QUINOLINES; ARENES; BENZODIAZINES;

D O I：

10.1039/c2cc35701a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Onium amides, generated in situ from the combination of aminosilanes and onium fluorides (R4PF, R4NF), are employed for the first time as bases for catalytic deprotonative functionalization of C(sp(2))-H and activated C(sp(3))-H bonds under mild conditions.

引用

页码：9771 / 9773

页数：3

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