Safety of viral DNA in biological products

被引：9

作者：

Krause, PR ^{[1
]}

Lewis, AM ^{[1
]}

机构：

[1] US FDA, Off Vaccines Res & Rev, Ctr Biol Evaluat & Res, Bethesda, MD 20014 USA

来源：

BIOLOGICALS | 1998年 / 26卷 / 04期

关键词：

D O I：

10.1006/biol.1998.0161

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Data from studies of the infectivity of DNA injected directly into laboratory animals are used to estimate the potential infectivity risk of residual DNA in biological products. The potential for some novel products to contain infectious quantities of residual cellular DNA is discussed, and further study of this subject is suggested. (C) 1998 The International Association of Biological Standardization.

引用

页码：317 / 320

页数：4

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