Artificial Apnea Classification with Quantitative Sleep EEG Synchronization

被引:23
作者
Aksahin, Mehmet [2 ]
Aydin, Serap [1 ]
Firat, Hikmet [3 ]
Erogul, Osman [4 ]
机构
[1] Ondokuz Mayis Univ, Fac Engn, Dept Elect & Elect Engn, Samsun, Turkey
[2] Baskent Univ, Dept Biomed Engn, TR-06490 Ankara, Turkey
[3] Diskapi Yildirim Beyazit Instruct & Exploratory H, Sleep Lab, Ankara, Turkey
[4] Gulhane Mil Med Acad, Biomed & Clin Engn Ctr, Ankara, Turkey
关键词
Sleep EEG; Apnea; EEG classification; Mutual information; Coherence function;
D O I
10.1007/s10916-010-9453-8
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
In the present study, both linear and nonlinear EEG synchronization methods so called Coherence Function (CF) and Mutual Information (MI) are performed to obtain high quality signal features in discriminating the Central Sleep Apnea (CSA) and Obstructive Sleep Apnea (OSA) from controls. For this purpose, sleep EEG series recorded from patients and healthy volunteers are classified by using several Feed Forward Neural Network (FFNN) architectures with respect to synchronic activities between C3 and C4 recordings. Among the sleep stages, stage2 is considered in tests. The NN approaches are trained with several numbers of neurons and hidden layers. The results show that the degree of central EEG synchronization during night sleep is closely related to sleep disorders like CSA and OSA. The MI and CF give us cooperatively meaningful information to support clinical findings. Those three groups determined with an expert physician can be classified by addressing two hidden layers with very low absolute error where the average area of CF curves ranged form 0 to 10 Hz and the average MI values are assigned as two features. In a future work, these two features can be combined to create an integrated single feature for error free apnea classification.
引用
收藏
页码:139 / 144
页数:6
相关论文
共 34 条
[1]  
Ali A. N., 2009, ADV BIOSIGNAL PROCES, P8, DOI [10.1007/978-3-540-89506-0, DOI 10.1007/978-3-540-89506-0]
[2]   Improving diagnostic ability of blood oxygen saturation from overnight pulse oximetry in obstructive sleep apnea detection by means of central tendency measure [J].
Alvarez, Daniel ;
Hornero, Roberto ;
Garcia, Maria ;
del Campo, Felix ;
Zamarron, Carlos .
ARTIFICIAL INTELLIGENCE IN MEDICINE, 2007, 41 (01) :13-24
[3]   Singular Spectrum Analysis of Sleep EEG in Insomnia [J].
Aydin, Serap ;
Saraoglu, Hamdi Melih ;
Kara, Sadik .
JOURNAL OF MEDICAL SYSTEMS, 2011, 35 (04) :457-461
[4]   Computer Based Synchronization Analysis on Sleep EEG in Insomnia [J].
Aydin, Serap .
JOURNAL OF MEDICAL SYSTEMS, 2011, 35 (04) :517-520
[5]   Determination of autoregressive model orders for seizure detection [J].
Aydin, Serap .
TURKISH JOURNAL OF ELECTRICAL ENGINEERING AND COMPUTER SCIENCES, 2010, 18 (01) :23-30
[6]   Comparison of Power Spectrum Predictors in Computing Coherence Functions for Intracortical EEG Signals [J].
Aydin, Serap .
ANNALS OF BIOMEDICAL ENGINEERING, 2009, 37 (01) :192-200
[7]   The synchronization of chaotic systems [J].
Boccaletti, S ;
Kurths, J ;
Osipov, G ;
Valladares, DL ;
Zhou, CS .
PHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS, 2002, 366 (1-2) :1-101
[8]   FAST TRAINING ALGORITHMS FOR MULTILAYER NEURAL NETS [J].
BRENT, RP .
IEEE TRANSACTIONS ON NEURAL NETWORKS, 1991, 2 (03) :346-354
[9]  
Bronzino J. D., 2000, BIOMEDICAL ENG HDB, P15
[10]  
Culebras A., 1996, CLIN HDB SLEEP DISOR