Preparation of monodisperse poly(N-isopropylacrylamide) microspheres and microcapsules via Shirasu-porous-glass membrane emulsification

被引：21

作者：

Cheng, Chang-Jing ^{[1
]}

Chu, Liang-Yin ^{[1
]}

Zhang, Jie ^{[1
]}

Zhou, Ming-Yu ^{[1
]}

Xie, Rui ^{[1
]}

机构：

[1] Sichuan Univ, Sch Chem Engn, Chengdu 610065, Sichuan, Peoples R China

来源：

DESALINATION | 2008年 / 234卷 / 1-3期

基金：

中国国家自然科学基金;

关键词：

Microspheres; Microcapsules; Monodispersity; SPG membrane emulsification; UV polymerization; Poly(N-isopropylacrylamide);

D O I：

10.1016/j.desal.2007.09.085

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

We have successfully prepared monodisperse poly(N-isopropylacrylamide) (PNIPAM) microspheres and hollow microcapsules by employing monomer-contained water-in-oil (W/O) emulsions as the polymerizing templates and introducing proper initiators into the disperse water phase or continuous oil phase, respectively. First, monodisperse monomer-contained W/O emulsions were prepared by SPG membrane emulsification method; then, UV irradiation was used to polymerize the monomer-contained W/O emulsions at a temperature below the lower critical solution temperature of PNIPAM. The prepared PNIPAM microspheres and hollow microcapsules were featured with good monodispersity and excellent thermo-responsive properties. The preparation methodology demonstrated in this study provided a unique approach for preparing monodisperse microspheres and hollow microcapsules with single W/O emulsions.

引用

页码：184 / 194

页数：11

共 25 条

[11] METHYLPHENAZONIUM-MODIFIED ENZYME SENSOR-BASED ON POLYMER THICK-FILMS FOR SUBNANOMOLAR DETECTION OF PHENOLS [J].

KOTTE, H ;

GRUNDIG, B ;

VORLOP, KD ;

STREHLITZ, B ;

STOTTMEISTER, U .

ANALYTICAL CHEMISTRY, 1995, 67 (01) :65-70

[12] Photoinitiated, inverse emulsion polymerization of acrylamide: Some mechanistic and kinetic aspects [J].

Liu, LY ;

Yang, WT .

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2004, 42 (04) :846-852

[13] Effects of the reaction parameters on the properties of thermosensitive poly(N-isopropylacrylamide) microspheres prepared by precipitation and dispersion polymerization [J].

Macková, H ;

Horák, D .

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2006, 44 (02) :968-982

[14] Particle control of emulsion by membrane emulsification and its applications [J].

Nakashima, T ;

Shimizu, M ;

Kukizaki, M .

ADVANCED DRUG DELIVERY REVIEWS, 2000, 45 (01) :47-56

[15] A POLYMER GEL WITH ELECTRICALLY DRIVEN MOTILITY [J].

OSADA, Y ;

OKUZAKI, H ;

HORI, H .

NATURE, 1992, 355 (6357) :242-244

[16] DESWELLING CHARACTERISTICS OF POLY(N-ISOPROPYLACRYLAMIDE) HYDROGEL [J].

PARK, TG ;

HOFFMAN, AS .

JOURNAL OF APPLIED POLYMER SCIENCE, 1994, 52 (01) :85-89

[17] Environment-sensitive hydrogels for drug delivery [J].

Qiu, Y ;

Park, K .

ADVANCED DRUG DELIVERY REVIEWS, 2001, 53 (03) :321-339

[18] Rapid deswelling of porous poly(N-isopropylacrylamide) hydrogels prepared by incorporation of silica particles [J].

Serizawa, T ;

Wakita, K ;

Akashi, M .

MACROMOLECULES, 2002, 35 (01) :10-12

[19] Preparation of W/O emulsion by membrane emulsification and optimum conditions for its monodispersion [J].

Shimizu, M ;

Nakashima, T ;

Kukizaki, M .

KAGAKU KOGAKU RONBUNSHU, 2002, 28 (03) :310-316

[20] Synthesis and characterization of injectable poly(N-isopropylacrylamide)-based hydrogels that support tissue formation in vitro [J].

Stile, RA ;

Burghardt, WR ;

Healy, KE .

MACROMOLECULES, 1999, 32 (22) :7370-7379

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