Optically Responsive and Mechanically Tunable Colloid-In-Liquid Crystal Gels that Support Growth of Fibroblasts

被引:38
作者
Agarwal, Ankit [1 ]
Huang, Elise [1 ]
Palecek, Sean [1 ]
Abbott, Nicholas L. [1 ]
机构
[1] Univ Wisconsin, Dept Chem & Biol Engn, Madison, WI 53706 USA
关键词
D O I
10.1002/adma.200800932
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Whereas low molecular weight liquid crystals (LCs) are too soft to support the culture of fibroblast cells, gels formed by polystyrene microparticles dispersed in LCs can be mechanically tuned to support the cell culture. These self-supporting gels can be readily molded, thus facilitating their use for cell culture, and they contain micrometer-sized domains of LCs that can be oriented by interactions at the surfaces confining the gels.
引用
收藏
页码:4804 / +
页数:7
相关论文
共 27 条
  • [1] Cellular solid behaviour of liquid crystal colloids - 1. Phase separation and morphology
    Anderson, VJ
    Terentjev, EM
    Meeker, SP
    Crain, J
    Poon, WCK
    [J]. EUROPEAN PHYSICAL JOURNAL E, 2001, 4 (01) : 11 - 20
  • [2] Biomolecular interactions at phospholipid-decorated surfaces of liquid crystals
    Brake, JM
    Daschner, MK
    Luk, YY
    Abbott, NL
    [J]. SCIENCE, 2003, 302 (5653) : 2094 - 2097
  • [3] Effect of surfactant structure on the orientation of liquid crystals at aqueous-liquid crystal interfaces
    Brake, JM
    Mezera, AD
    Abbott, NL
    [J]. LANGMUIR, 2003, 19 (16) : 6436 - 6442
  • [4] An experimental system for imaging the reversible adsorption of amphiphiles at aqueous-liquid crystal interfaces
    Brake, JM
    Abbott, NL
    [J]. LANGMUIR, 2002, 18 (16) : 6101 - 6109
  • [5] Network formation in colloid-liquid crystal mixtures studied by confocal microscopy
    Cleaver, J
    Poon, WCK
    [J]. JOURNAL OF PHYSICS-CONDENSED MATTER, 2004, 16 (19) : S1901 - S1909
  • [6] COGNARD J, 1982, MOL CRYST LIQ CRYST, P1
  • [7] Measuring the elastic modulus of small tissue samples
    Erkamp, RQ
    Wiggins, P
    Skovoroda, AR
    Emelianov, SY
    O'Donnell, M
    [J]. ULTRASONIC IMAGING, 1998, 20 (01) : 17 - 28
  • [8] Imaging biological cells using liquid crystals
    Fang, JY
    Ma, W
    Selinger, JV
    Shashidhar, R
    [J]. LANGMUIR, 2003, 19 (07) : 2865 - 2869
  • [9] Cell type-specific response to growth on soft materials
    Georges, PC
    Janmey, PA
    [J]. JOURNAL OF APPLIED PHYSIOLOGY, 2005, 98 (04) : 1547 - 1553
  • [10] Optical amplification of ligand-receptor binding using liquid crystals
    Gupta, VK
    Skaife, JJ
    Dubrovsky, TB
    Abbott, NL
    [J]. SCIENCE, 1998, 279 (5359) : 2077 - 2080