Autologous HSCT is efficacious, but can we make it safer?

被引：27
作者：
Burt, Richard K. [1 ]
Farge, Dominique [2 ]
机构：
[1] Northwestern Univ, Dept Med, Feinberg Sch Med, Div Immunotherapy, Chicago, IL 60611 USA
[2] Univ Paris 07, Hop St Louis, AP HP, Unite Clin Med Interne Malad Autoimmunes & Pathol, Paris, France
来源：
NATURE REVIEWS RHEUMATOLOGY | 2018年 / 14卷 / 04期
关键词：
STEM-CELL TRANSPLANTATION; SYSTEMIC-SCLEROSIS; PULSE CYCLOPHOSPHAMIDE; AUTOIMMUNE-DISEASES; WORKING PARTY; BLOOD;
D O I：
10.1038/nrrheum.2018.34
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Autologous haematopoietic stem cell transplantation (HSCT) has proved efficacious in treating patients with systemic sclerosis, but different regimens have different associated toxicities and different effects on lung function. Through comparison of different clinical trials, we can learn how to improve the safety of HSCT.
引用
收藏
页码：191 / 192
页数：2
相关论文
共 9 条
  • [1] Cardiac Assessment Before Stem Cell Transplantation for Systemic Sclerosis
    Burt, Richard K.
    Oliveira, Maria Carolina
    Shah, Sanjiv J.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2014, 312 (17): : 1803 - 1803
  • [2] Cardiac involvement and treatment-related mortality after non-myeloablative haemopoietic stem-cell transplantation with unselected autologous peripheral blood for patients with systemic sclerosis: a retrospective analysis
    Burt, Richard K.
    Oliveira, Maria Carolina
    Shah, Sanjiv J.
    Moraes, Daniela A.
    Simoes, Belinda
    Gheorghiade, Mihai
    Schroeder, James
    Ruderman, Eric
    Farge, Dominique
    Chai, Z. Jessie
    Marjanovic, Zora
    Jain, Sandeep
    Morgan, Amy
    Milanetti, Francesca
    Han, Xiaoqiang
    Jovanovic, Borko
    Helenowski, Irene B.
    Voltarelli, Julio
    [J]. LANCET, 2013, 381 (9872) : 1116 - 1124
  • [3] Hematopoietic Stem Cell Transplantation for Systemic Sclerosis: If You Are Confused, Remember: "It Is a Matter of the Heart"
    Burt, Richard K.
    Shah, Sanjiv J.
    Gheorghiade, Mihai
    Ruderman, Eric
    Schroeder, James
    [J]. JOURNAL OF RHEUMATOLOGY, 2012, 39 (02) : 206 - 209
  • [4] Autologous non-myeloablative haemopoietic stem-cell transplantation compared with pulse cyclophosphamide once per month for systemic sclerosis (ASSIST): an open-label, randomised phase 2 trial
    Burt, Richard K.
    Shah, Sanjiv J.
    Dill, Karin
    Grant, Thomas
    Gheorghiade, Mihai
    Schroeder, James
    Craig, Robert
    Hirano, Ikuo
    Marshall, Karin
    Ruderman, Eric
    Jovanovic, Borko
    Milanetti, Francesca
    Jain, Sandeep
    Boyce, Kristin
    Morgan, Amy
    Carr, James
    Barr, Walter
    [J]. LANCET, 2011, 378 (9790) : 498 - 506
  • [5] Cardiopulmonary assessment of patients with systemic sclerosis for hematopoietic stem cell transplantation: recommendations from the European Society for Blood and Marrow Transplantation Autoimmune Diseases Working Party and collaborating partners
    Farge, D.
    Burt, R. K.
    Oliveira, M-C
    Mousseaux, E.
    Rovira, M.
    Marjanovic, Z.
    de Vries-Bouwstra, J.
    Del Papa, N.
    Saccardi, R.
    Shah, S. J.
    Lee, D. C.
    Denton, C.
    Alexander, T.
    Kiely, D. G.
    Snowden, J. A.
    [J]. BONE MARROW TRANSPLANTATION, 2017, 52 (11) : 1495 - 1503
  • [6] Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years' experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases
    Farge, Dominique
    Labopin, Myriam
    Tyndall, Alan
    Fassas, Athanasios
    Mancardi, Gian Luigi
    Van Laar, Jaap
    Jian Ouyang
    Kozak, Tomas
    Moore, John
    Koetter, Ina
    Chesnel, Virginie
    Marmont, Alberto
    Gratwohl, Alois
    Saccardi, Riccardo
    [J]. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010, 95 (02): : 284 - 292
  • [7] Snowden J. A, BLOOD ADV, V1
  • [8] Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma
    Sullivan, K. M.
    Goldmuntz, E. A.
    Keyes-Elstein, L.
    McSweeney, P. A.
    Pinckney, A.
    Welch, B.
    Mayes, M. D.
    Nash, R. A.
    Crofford, L. J.
    Eggleston, B.
    Castina, S.
    Griffith, L. M.
    Goldstein, J. S.
    Wallace, D.
    Craciunescu, O.
    Khanna, D.
    Folz, R. J.
    Goldin, J.
    Clair, E. W. St.
    Seibold, J. R.
    Phillips, K.
    Mineishi, S.
    Simms, R. W.
    Ballen, K.
    Wener, M. H.
    Georges, G. E.
    Heimfeld, S.
    Hosing, C.
    Forman, S.
    Kafaja, S.
    Silver, R. M.
    Griffing, L.
    Storek, J.
    LeClercq, S.
    Brasington, R.
    Csuka, M. E.
    Bredeson, C.
    Keever-Taylor, C.
    Domsic, R. T.
    Kahaleh, M. B.
    Medsger, T.
    Furst, D. E.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2018, 378 (01) : 35 - 47
  • [9] Autologous Hematopoietic Stem Cell Transplantation vs Intravenous Pulse Cyclophosphamide in Diffuse Cutaneous Systemic Sclerosis A Randomized Clinical Trial
    van Laar, Jacob M.
    Farge, Dominique
    Sont, Jacob K.
    Naraghi, Kamran
    Marjanovic, Zora
    Larghero, Jerome
    Schuerwegh, Annemie J.
    Marijt, Erik W. A.
    Vonk, Madelon C.
    Schattenberg, Anton V.
    Matucci-Cerinic, Marco
    Voskuyl, Alexandre E.
    van de Loosdrecht, Arjan A.
    Daikeler, Thomas
    Koetter, Ina
    Schmalzing, Marc
    Martin, Thierry
    Lioure, Bruno
    Weiner, Stefan M.
    Kreuter, Alexander
    Deligny, Christophe
    Durand, Jean-Marc
    Emery, Paul
    Machold, Klaus R.
    Sarrot-Reynauld, Francoise
    Warnatz, Klaus
    Adoue, Daniel F. P.
    Constans, Joel
    Tony, Hans-Peter
    Del Papa, Nicoletta
    Fassas, Athanasios
    Himsel, Andrea
    Launay, David
    Lo Monaco, Andrea
    Philippe, Pierre
    Quere, Isabelle
    Rich, Eric
    Westhovens, Rene
    Griffiths, Bridget
    Saccardi, Riccardo
    van den Hoogen, Frank H.
    Fibbe, Willem E.
    Socie, Gerard
    Gratwohl, Alois
    Tyndall, Alan
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2014, 311 (24): : 2490 - 2498
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