Comparative Study for Determination of Mycobacterium tuberculosis Susceptibility to First- and Second-Line Antituberculosis Drugs by the Etest Using 7H11, Blood, and Chocolate Agar

被引：9

作者：

Coban, Ahmet Yilmaz ^{[1
]}

Bilgin, Kemal ^{[1
]}

Uzun, Meltem ^{[2
]}

Akgunes, Alper ^{[1
,3
]}

Yusof, Anne ^{[4
]}

Durupinar, Belma ^{[1
]}

机构：

[1] Ondokuz Mayis Univ, Sch Med, Dept Microbiol & Clin Microbiol, TR-55139 Samsun, Turkey

[2] Istanbul Univ, Istanbul Med Sch, Dept Microbiol & Clin Microbiol, Istanbul, Turkey

[3] Chest Dis Hosp, Mycobacteriol Lab, Samsun, Turkey

[4] AB Biodisk Res Labs, S-16956 Solna, Sweden

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2008年 / 46卷 / 12期

关键词：

D O I：

10.1128/JCM.01104-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We investigated the performance of blood and chocolate agar as alternatives to Middlebrook 7H11 agar for testing the susceptibility of Mycobacterium tuberculosis to first-and second-line drugs by the Etest method. A total of 39 strains of M. tuberculosis including 22 multidrug-resistant M. tuberculosis strains and 17 susceptible strains were tested. In conclusion, our results showed that chocolate agar gave insufficient growth, needing up to 21 days of incubation, while results on blood agar were comparable to those on Middlebrook 7H11 agar and can be further explored as an alternative for Etest-based susceptibility testing of M. tuberculosis.

引用

页码：4095 / 4098

页数：4

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