Linear IgA bullous dermatosis

被引:18
作者
Juratli, H. A. [1 ]
Sardy, M. [2 ]
机构
[1] Univ Klinikum Giessen & Marburg, Klin Dermatol & Allergol, Baldingerstr 1, D-35043 Marburg, Germany
[2] Semmelweis Univ, Fak Med, Klin Dermatol Venerol & Dermatoonkol, Budapest, Hungary
来源
HAUTARZT | 2019年 / 70卷 / 04期
关键词
Diagnostics; Therapy; Autoantibodies; Pathogenesis; Autoimmune dermatosis; DISEASE; ANTIBODIES; CHILDHOOD; DIAGNOSIS; ANTIGENS;
D O I
10.1007/s00105-019-4377-9
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Linear IgA bullous dermatosis is arare autoimmune blistering disease that occurs in both children and adults. Strings of pearls, crowns of jewels, rosettes and urticarial plaques can occur on the whole integument with emphasis on the face (particularly perioral area) and genitalia. Pruritus is common and may be severe. The presence of IgA deposits along the basement membrane can usually be identified using direct immunofluorescence (DIF) microscopy. The histological and clinical features of this disorder may mimic those of dermatitis herpetiformis.
引用
收藏
页码:254 / 259
页数:6
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