Arsenic trioxide in the treatment of advanced acute promyelocytic leukemia

被引:0
|
作者
Carmosino, I
Latagliata, R
Avvisati, G
Breccia, M
Finolezzi, E
Lo Coco, F
Petti, MC
机构
[1] Univ Roma La Sapienza, Dipartimento Biotecnol Umane & Ematol, I-00161 Rome, Italy
[2] Ist Regina Elena, IFO, I-00161 Rome, Italy
关键词
arsenic trioxide; acute promyelocytic leukemia;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Eleven patients with advanced APL were treated with ATO (0.15 mg/Kg daily). Eight (73%) achieved molecular CR, but 5 relapsed, 1 died in molecular CR, 1 was lost to follow-up and 1 is still alive in CR after allogeneic transplantation. We suggest that ATO may be effective also in advanced APL, but given the short CR, it seems indicated only in patients eligible for transplant procedures.
引用
收藏
页码:615 / 617
页数:3
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