Cancer incidence in Dutch Balkan veterans

被引:19
作者
Bogers, Rik P. [1 ]
van Leeuwen, Flora E. [2 ]
Grievink, Linda [1 ]
Schouten, Leo J. [3 ]
Kiemeney, Lambertus A. L. M. [4 ]
Schram-Bijkerk, Dieneke [1 ]
机构
[1] Natl Inst Publ Hlth & Environm, NL-3720 BA Bilthoven, Netherlands
[2] Netherlands Canc Inst, Dept Epidemiol, NL-1006 BE Amsterdam, Netherlands
[3] Maastricht Univ, Dept Epidemiol, GROW Sch Oncol & Dev Biol, NL-6200 MD Maastricht, Netherlands
[4] Radboud Univ Nijmegen, Med Ctr, NL-6500 HB Nijmegen, Netherlands
关键词
Cohort studies; Historical; Incidence; Military personnel; Neoplasms; Occupational exposure; GULF-WAR; FOLLOW-UP; SURVEILLANCE; PERSONNEL;
D O I
10.1016/j.canep.2013.04.005
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Suspicion has been raised about an increased cancer risk among Balkan veterans because of alleged exposure to depleted uranium. The authors conducted a historical cohort study to examine cancer incidence among Dutch Balkan veterans. Male military personnel (n = 18,175, median follow-up 11 years) of the Army and Military Police who had been deployed to the Balkan region (1993-2001) was compared with their peers not deployed to the Balkans (n = 135,355, median follow-up 15 years) and with the general Dutch population of comparable age and sex. The incidence of all cancers and 4 main cancer subgroups was studied in the period 1993-2008. The cancer incidence rate among Balkan deployed military men was 17% lower than among non-Balkan deployed military men (hazard ratio 0.83 (95% confidence interval 0.69, 1.00)). For the 4 main cancer subgroups, hazard ratios were statistically non-significantly below 1. Also compared to the general population cancer rates were lower in Balkan deployed personnel (standardised incidence rate ratio (SIR) 0.85 (0.73, 0.99). The SIR for leukaemia was 0.63 (0.20, 1.46). The authors conclude that earlier suggestions of increased cancer risks among veterans are not supported by empirical data. The lower risk of cancer might be explained by the 'healthy warrior effect'. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:550 / 555
页数:6
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