DNA variants in the human RAB3A gene are not associated with autism

被引：1
作者：
D'Adamo, P
Bacchelli, E
Blasi, F
Lipp, HP
Toniolo, D
Maestrini, E
机构：
[1] Univ Zurich, Inst Anat, CH-8057 Zurich, Switzerland
[2] Univ Bologna, Dipartimento Biol Evoluz Sperimentale, Bologna, Italy
[3] DIBIT, Ist Sci San Raffaele, Milan, Italy
来源：
GENES BRAIN AND BEHAVIOR | 2004年 / 3卷 / 02期
关键词：
ADHD; autism; human; mouse; mutation; Rab3a;
D O I：
10.1111/j.1601-183X.2003.00058.x
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
Mutation screening of the RAB3A gene in 47 individuals with autism provided no evidence that DNA variants in this gene are associated with autism. Since Rab3a constitutive knockout mice react to novel stimuli with hyperactivity, a further search for association of RAB3A DNA variants with other neurobehavioral disorders such as attention deficit/hyperactivity disorder appears justified.
引用
收藏
页码：123 / 124
页数：2
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