A Novel Method for the One-pot Five-component Synthesis of Highly Functionalized Pyranopyrazoles Catalyzed by CuI Nanoparticles

被引：0

作者：

Safaei-Ghomi, Javad ^{[1
]}

Ziarati, Abolfazl ^{[1
]}

Tamimi, Mehrnoush ^{[2
]}

机构：

[1] Univ Kashan, Dept Organ Chem, Fac Chem, Kashan 51167, Iran

[2] Islamic Azad Univ, Dept Chem, Qom Branch, Qom, Iran

来源：

ACTA CHIMICA SLOVENICA | 2013年 / 60卷 / 02期

关键词：

Pyranopyrazoles; one pot; five-component reaction; in situ preparation; CuI nanoparticles; NANOCRYSTALLINE MGO; MULTICOMPONENT SYNTHESIS; ORGANIC-SYNTHESIS; MELDRUMS ACID; SOLVENT-FREE; ZNO NANOPARTICLES; REUSABLE CATALYST; MILD CONDITIONS; AQUEOUS-MEDIA; DERIVATIVES;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel one-pot, five-component reaction for the synthesis of highly functionalized pyranopyrazoles from acid chlorides, Meldrum's acid, hydrazine hydrate, aromatic aldehydes and malononitrile in the presence of catalytic amount of CuI nanoparticles in aqueous media is reported. This method provides several benefits such as in situ preparation of beta-ketoester, mild reaction conditions, and environmentally friendly, waste-free and simple work-up procedure with excellent yields. The catalyst could be recovered and reused for several times with almost consistent catalytic activity.

引用

页码：403 / 410

页数：8

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