Effects of Alcohol on the Endocrine System

被引:78
|
作者
Rachdaoui, Nadia [1 ]
Sarkar, Dipak K. [1 ]
机构
[1] Rutgers State Univ, Dept Anim Sci, Rutgers Endocrine Res Program, New Brunswick, NJ 08901 USA
关键词
Alcoholism; Endocrine disorders; Circadian dysfunction; Immune abnormalities; CORTICOTROPIN-RELEASING-FACTOR; GROWTH-FACTOR-I; PITUITARY-THYROID AXIS; ETHANOL-INDUCED ALTERATIONS; FEMALE RHESUS-MONKEY; LUTEINIZING-HORMONE; CIRCADIAN CLOCK; ADRENAL AXIS; TESTICULAR FUNCTION; INDUCED SUPPRESSION;
D O I
10.1016/j.ecl.2013.05.008
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chronic consumption of a large amount of alcohol disrupts the communication between nervous, endocrine, and immune system and causes hormonal disturbances that lead to profound and serious consequences at physiologic and behavioral levels. These alcohol-induced hormonal dysregulations affect the entire body and can result in various disorders such as stress abnormalities, reproductive deficits, body growth defect, thyroid problems, immune dysfunction, cancers, bone disease, and psychological and behavioral disorders. This review summarizes the findings from human and animal studies that provide consistent evidence on the various effects of alcohol abuse on the endocrine system.
引用
收藏
页码:593 / +
页数:24
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