Role of surgery in the management of head and neck cancer: a contemporary view of the data in the era of organ preservation

被引:20
作者
Hoermann, K. [1 ]
Sadick, H. [1 ]
机构
[1] Univ Hosp Mannheim, Dept Otolaryngol Head & Neck Surg, D-68135 Mannheim, Germany
关键词
Head And Neck Neoplasms; General Surgery; Organ Preservation; Survival; SQUAMOUS-CELL CARCINOMA; TRANSORAL LASER MICROSURGERY; LOCALLY ADVANCED HEAD; RADIATION-THERAPY; DEFINITIVE RADIOTHERAPY; CONCURRENT CHEMOTHERAPY; HYPOPHARYNGEAL CANCER; LARYNX-PRESERVATION; GLOTTIC CARCINOMA; UNITED-STATES;
D O I
10.1017/S0022215112002988
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Objective: Review of the literature on the role of surgery in the management of head and neck cancer in the era of organ preservation. Method: Literature search based on the essential practice guidelines set out by the US National Comprehensive Cancer Network. Results: Despite the increasing popularity of non-surgical treatment options, the surgeon remains a key figure in the multidisciplinary head and neck cancer team, along with the radiation oncologist, the medical oncologist and the speech and swallowing therapist. Even when organ preservation is successful, early and late toxicity may cause serious complications, including laryngeal dysfunction with a 'frozen larynx'. When organ preservation fails, salvage surgery is often associated with increased complications and reduced survival. Conclusion: There is a definite need to apply more rigorous standards to the use of organ preservation strategies, and to re-evaluate the role of surgery in head and neck cancer treatment.
引用
收藏
页码:121 / 127
页数:7
相关论文
共 73 条
[1]  
Adelstein DJ, 1997, HEAD NECK-J SCI SPEC, V19, P567, DOI 10.1002/(SICI)1097-0347(199710)19:7<567::AID-HED2>3.3.CO
[2]  
2-N
[3]  
Ambrosch P, 2011, Laryngorhinootologie, V90 Suppl 1, pS83, DOI 10.1055/s-0030-1270449
[4]  
Ambrosch P., 2001, Onkologe, V7, P505, DOI DOI 10.1007/S007610170103
[5]  
ARRIAGADA R, 1983, CANCER-AM CANCER SOC, V51, P1819, DOI 10.1002/1097-0142(19830515)51:10<1819::AID-CNCR2820511011>3.0.CO
[6]  
2-G
[7]   Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer [J].
Bernier, J ;
Domenge, C ;
Ozsahin, M ;
Matuszewska, K ;
Lefèbvre, JL ;
Greiner, RH ;
Giralt, J ;
Maingon, P ;
Rolland, F ;
Bolla, M ;
Cognetti, F ;
Bourhis, J ;
Kirkpatrick, A ;
van Glabbeke, M .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (19) :1945-1952
[8]   Total pharyngolaryngectomy for squamous cell carcinoma of the hypopharynx: A review [J].
Bova, R ;
Goh, R ;
Poulson, M ;
Coman, WB .
LARYNGOSCOPE, 2005, 115 (05) :864-869
[9]   Trends in incidence and prognosis for head and neck cancer in the United States: A site-specific analysis of the SEER database [J].
Carvalho, AL ;
Nishimoto, IN ;
Califano, JA ;
Kowalski, LP .
INTERNATIONAL JOURNAL OF CANCER, 2005, 114 (05) :806-816
[10]  
Chevalier D, 1997, HEAD NECK-J SCI SPEC, V19, P1, DOI 10.1002/(SICI)1097-0347(199701)19:1<1::AID-HED1>3.0.CO