Myasthenia gravis activities of daily living profile

被引:372
作者
Wolfe, GI
Herbelin, L
Nations, SP
Foster, B
Bryan, WW
Barohn, RJ
机构
[1] Univ Texas, SW Med Ctr, Dept Neurol, Dallas, TX 75235 USA
[2] Univ Texas, SW Med Ctr Acad Comp Serv, Dallas, TX 75235 USA
关键词
D O I
10.1212/WNL.52.7.1487
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors have developed an MG activities of daily living (ADL) profile (MG-ADL)-a simple eight-question survey of MG symptoms. In 254 consecutive encounters with established MG patients, the authors compared scores from the MG-ADL to the quantitative MG score (QMG)-a standardized, reliable scale used in clinical trials. The mean MG-ADL score was 4.89 +/- 3.63. The mean QMG score was 10.80 +/- 5.70. Pearson's correlation coefficient was 0.583 (p < 0.001). The MG-ADL is an easy-to-administer survey of MG that correlates well with the QMG and can serve as a secondary efficacy measurement in clinical trials.
引用
收藏
页码:1487 / 1489
页数:3
相关论文
共 7 条
  • [1] Reliability testing of the quantitative myasthenia gravis score
    Barohn, RJ
    McIntire, D
    Herbelin, L
    Wolfe, GI
    Nations, S
    Bryan, WW
    [J]. MYASTHENIA GRAVIS AND RELATED DISEASES: DISORDERS OF THE NEUROMUSCULAR JUNCTION, 1998, 841 : 769 - 772
  • [2] MYASTHENIA-GRAVIS - LONG-TERM CORRELATION OF BINDING AND BUNGAROTOXIN BLOCKING ANTIBODIES AGAINST ACETYLCHOLINE-RECEPTORS WITH CHANGES IN DISEASE SEVERITY
    BESINGER, UA
    TOYKA, KV
    HOMBERG, M
    HEININGER, K
    HOHLFELD, R
    FATEHMOGHADAM, A
    [J]. NEUROLOGY, 1983, 33 (10) : 1316 - 1321
  • [3] Long-term outcome and quality of life after thymectomy for myasthenia gravis
    Busch, C
    Machens, A
    Pichlmeier, U
    Emskotter, T
    Izbicki, JR
    [J]. ANNALS OF SURGERY, 1996, 224 (02) : 225 - 232
  • [4] Relationship of the Tufts Quantitative Neuromuscular Exam (TQNE) and the Sickness Impact Profile (SIP) in measuring progression of ALS
    McGuire, D
    Garrison, L
    Armon, C
    Barohn, R
    Bryan, W
    Miller, R
    Parry, G
    Petajan, J
    Ross, M
    Alternus, P
    Amox, D
    Ashburn, C
    Aulenbacher, D
    Blasucci, L
    Brown, E
    Caulkins, M
    Carozza, C
    Dao, H
    Davis, L
    Driscoll, T
    Frierson, L
    Fuqua, P
    Gardner, H
    Golbesky, B
    Good, B
    Graves, J
    Harstock, L
    Hawkins, C
    Hernandez, R
    Iturriaga, E
    Kres, J
    Laurenzi, B
    Lee, E
    Leyde, D
    Mehagian, M
    Moses, D
    Nash, J
    Norwood, N
    Parsons, J
    Pearmain, J
    RatliffWalker, D
    Rightmyer, D
    Rizzi, V
    Smith, B
    Soliman, M
    Volintine, L
    Warder, J
    Werner, J
    Wolf, S
    [J]. NEUROLOGY, 1996, 46 (05) : 1442 - 1444
  • [5] Osserman K, 1958, MYASTHENIA GRAVIS
  • [6] MYASTHENIA-GRAVIS - QUANTITATIVE-EVALUATION SYSTEM
    SZOBOR, A
    [J]. EUROPEAN NEUROLOGY, 1976, 14 (06) : 439 - 446
  • [7] PRELIMINARY-RESULTS OF A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL OF CYCLOSPORINE IN MYASTHENIA-GRAVIS
    TINDALL, RSA
    ROLLINS, JA
    PHILLIPS, JT
    GREENLEE, RG
    WELLS, L
    BELENDIUK, G
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1987, 316 (12) : 719 - 724