An overview of Neem (Azadirachta indica) and its potential impact on health

被引：126

作者：

Francisco Islas, Jose ^{[1
]}

Acosta, Ezeiza ^{[2
]}

G-Buentello, Zuca ^{[1
]}

Luis Delgado-Gallegos, Juan ^{[1
]}

Guadalupe Moreno-Trevino, Maria ^{[3
]}

Escalante, Bruno ^{[3
]}

Moreno-Cuevas, Jorge E. ^{[3
]}

机构：

[1] Univ Autonoma Nuevo Leon, Fac Med, Dept Bioquim & Med Mol, Ave Francisco I Madero & Dr Aguirre Pequeno Col M, San Nicolas De Los Garza 64460, Nuevo Leon, Mexico

[2] Tecnol Monterrey, Escuela Med & Ciencias Salud, Ave Morones Prieto 3000, Monterrey 64710, Nuevo Leon, Mexico

[3] Univ Monterrey, Ciencias Salud, Ave Ignacio Morones Prieto 4500 Pte, San Pedro Garza Garcia 66238, Nuevo Leon, Mexico

来源：

JOURNAL OF FUNCTIONAL FOODS | 2020年 / 74卷

关键词：

Neem extracts; Nutritional components; Systemic diseases; XENOBIOTIC-METABOLIZING ENZYMES; LEAF EXTRACT; CELL-PROLIFERATION; IN-VITRO; MAMMARY CARCINOGENESIS; LIMONOIDS AZADIRACHTIN; POUCH CARCINOGENESIS; ANTIOXIDANT ACTIVITY; OXIDATIVE STRESS; ANIMAL-MODEL;

D O I：

10.1016/j.jff.2020.104171

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Global health and medical practice seek to merge alternative medicine with evidence-based medicine for a better understanding of the metabolic process and its effects in the human body. An example is the use of complementary medicine like phytotherapy. Azadirachta indica (Neem), a tree originally from India and Myanmar, called by many "The village pharmacy" or "Divine tree" because of its many health properties. In recent times, Neem-derived extracts have been shown to work from anywhere from insect repellent, to supplements to lower inflammation, diabetic control, and even to combat cancer. Herein, we state the health benefits found in diverse compounds and extracts derived from Neem, highlighting the mechanisms and pathways in which Neem compounds produce their effects, while warning that the improper and unstandardized conditions to produce extracts can lead to health issues, particularly certain compounds might have damaging effects on the liver and kidneys.

引用

页数：13

共 109 条

[91] Antioxidant activity of phenolic components present in barks of Azadirachta indica, Terminalia arjuna, Acacia nilotica, and Eugenia jambolana Lam. trees [J].