The PRIMA (PRoton IMAging) collaboration: Development of a proton Computed Tomography apparatus

被引：33

作者：

Scaringella, M. ^{[1
]}

Brianzi, M. ^{[2
]}

Bruzzi, M. ^{[2
,3
]}

Bucciolini, M. ^{[2
,4
,12
]}

Carpinelli, M. ^{[10
,11
]}

Cirrone, G. A. P. ^{[5
]}

Civinini, C. ^{[2
]}

Cuttone, G. ^{[5
]}

Lo Presti, D. ^{[6
,7
]}

Pallotta, S. ^{[2
,4
,12
]}

Pugliatti, C. ^{[6
,7
]}

Randazzo, N. ^{[6
]}

Romano, F. ^{[8
,9
]}

Sipala, V. ^{[10
,11
]}

Stancampiano, C. ^{[5
]}

Talamonti, C. ^{[2
,4
,12
]}

Tesi, M. ^{[1
]}

Vanzi, E. ^{[12
]}

Zani, M. ^{[2
,4
,8
,9
]}

机构：

[1] Univ Florence, Dipartimento Ingn Ind, Florence, Italy

[2] Ist Nazl Fis Nucl, Sez Firenze, I-50125 Florence, Italy

[3] Univ Florence, Dipartimento Fis & Astron, Florence, Italy

[4] Univ Florence, Dipartimento Sci Biomed Sperimentali & Clin, Florence, Italy

[5] Ist Nazl Fis Nucl, Lab Nazl Sud, I-95129 Catania, Italy

[6] Ist Nazl Fis Nucl, Sez Catania, I-95129 Catania, Italy

[7] Univ Catania, Dipartimento Fis, Catania, Italy

[8] Ctr Studi & Ric, Rome, Italy

[9] Museo Stor Fis, Rome, Italy

[10] Univ Sassari, Dipartimento Chim & Farm, I-07100 Sassari, Italy

[11] Ist Nazl Fis Nucl, Sez Cagliari, Cagliari, Italy

[12] Azienda Osped Univ Careggi, SOD Fis Med, Florence, Italy

来源：

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 2013年 / 730卷

关键词：

pCT (proton Computed Tomography); Silicon microstrip; Calorimetry; CHARGED-PARTICLE; RADIOGRAPHY; DETECTOR;

D O I：

10.1016/j.nima.2013.05.181

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

This paper describes the development of a proton Computed Tomography (pCT) apparatus able to reconstruct a map of stopping power useful for accurate proton therapy treatment planning and patient positioning. This system is based on two main components: a silicon microstrip tracker and a YAG:Ce crystal calorimeter. Each proton trajectory is sampled by the tracker in four points: two upstream and two downstream the object under test; the particle residual energy is measured by the calorimeter. The apparatus is described in details together with a discussion on the characterization of the hardware under proton beams with energies up to 175 MeV. (C) 2013 Elsevier B.V. All rights reserved

引用

页码：178 / 183

页数：6

共 17 条

[1] Geant4 developments and applications [J].

Allison, J ;

Amako, K ;

Apostolakis, J ;

Araujo, H ;

Dubois, PA ;

Asai, M ;

Barrand, G ;

Capra, R ;

Chauvie, S ;

Chytracek, R ;

Cirrone, GAP ;

Cooperman, G ;

Cosmo, G ;

Cuttone, G ;

Daquino, GG ;

Donszelmann, M ;

Dressel, M ;

Folger, G ;

Foppiano, F ;

Generowicz, J ;

Grichine, V ;

Guatelli, S ;

Gumplinger, P ;

Heikkinen, A ;

Hrivnacova, I ;

Howard, A ;

Incerti, S ;

Ivanchenko, V ;

Johnson, T ;

Jones, F ;

Koi, T ;

Kokoulin, R ;

Kossov, M ;

Kurashige, H ;

Lara, V ;

Larsson, S ;

Lei, F ;

Link, O ;

Longo, F ;

Maire, M ;

Mantero, A ;

Mascialino, B ;

McLaren, I ;

Lorenzo, PM ;

Minamimoto, K ;

Murakami, K ;

Nieminen, P ;

Pandola, L ;

Parlati, S ;

Peralta, L .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2006, 53 (01) :270-278

[2] Construction, test and operation of a proton range radiography system [J].

Amaldi, U. ;

Bianchi, A. ;

Chang, Y-H. ;

Go, A. ;

Hajdas, W. ;

Malakhov, N. ;

Samarati, J. ;

Sauli, F. ;

Watts, D. .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2011, 629 (01) :337-344

[3]

[Anonymous], 1964, THEORY PRACTICE SCIN

[4] First results on proton radiography with nuclear emulsion detectors [J].

Braccini, S. ;

Ereditato, A. ;

Kreslo, I. ;

Moser, U. ;

Pistillo, C. ;

Studer, S. ;

Scampoli, P. ;

Coray, A. ;

Pedroni, E. .

JOURNAL OF INSTRUMENTATION, 2010, 5

[5] The Italian project for a proton imaging device [J].

Cirrone, G. A. P. ;

Candiano, G. ;

Cuttone, G. ;

Lo Nigro, S. ;

Lo Presti, D. ;

Randazzo, N. ;

Sipala, V. ;

Russo, M. ;

Aiello, S. ;

Bruzzi, M. ;

Menichelli, D. ;

Secringella, M. ;

Miglio, S. ;

Bucciolini, M. ;

Talamonti, C. ;

Pallotta, S. .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2007, 576 (01) :194-197

[6] Initial studies on proton computed tomography using a silicon strip detector telescope [J].

Johnson, L ;

Keeney, B ;

Ross, G ;

Sadrozinski, HFW ;

Seiden, A ;

Williams, DC ;

Zhang, L ;

Bashkirov, V ;

Schulte, RW ;

Shahnazi, K .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2003, 514 (1-3) :215-223

[7] PROTON RADIOGRAPHY [J].

KOEHLER, AM .

SCIENCE, 1968, 160 (3825) :303-&

[8] Reconstruction for proton computed tomography by tracing proton trajectories: A Monte Carlo study [J].

Li, TF ;

Liang, ZR ;

Singanallur, JV ;

Satogata, TJ ;

Williams, DC ;

Schulte, RW .

MEDICAL PHYSICS, 2006, 33 (03) :699-706

[9] Characterization of a Silicon Strip Detector and a YAG:Ce Calorimeter for a Proton Computed Radiography Apparatus [J].

Menichelli, David ;

Bruzzi, Mara ;

Bucciolini, Marta ;

Candiano, Giuliana ;

Cirrone, Giuseppe A. Pablo ;

Capineri, Lorenzo ;

Civinini, Carlo ;

Cuttone, Giacomo ;

Lo Presti, Domenico ;

Marrazzo, Livia ;

Pallotta, Stefania ;

Randazzo, Nunzio ;

Sipala, Valeria ;

Talamonti, Cinzia ;

Valentini, Samuela ;

Pieri, Stefano ;

Reggioli, Valentina ;

Brianzi, Mirko ;

Tesi, Mauro .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2010, 57 (01) :8-16

[10] SMALL-ANGLE MULTIPLE-SCATTERING AND SPATIAL-RESOLUTION IN CHARGED-PARTICLE TOMOGRAPHY [J].

MUSTAFA, AAM ;

JACKSON, DF .

PHYSICS IN MEDICINE AND BIOLOGY, 1981, 26 (03) :461-472

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