[1] Univ Texas Hlth Sci Ctr San Antonio, Dept Physiol, San Antonio, TX 78229 USA
[2] Univ Texas Hlth Sci Ctr San Antonio, Barshop Inst Longev & Aging Studies, San Antonio, TX 78229 USA
[3] Univ Arizona, Coll Med Phoenix, Banner Sun Hlth Res Inst, Sun City, AZ 85351 USA
[4] Univ Arizona, Coll Med Phoenix, Dept Basic Med Sci, Sun City, AZ 85351 USA