Vigilance for veterinary medicinal products: Declarations of suspected adverse reactions in the year 2007

被引：7
|
作者：
Muentener, C. R. [1 ,2 ]
Bruckner, L. [3 ]
Stuerer, A. [4 ]
Althaus, F. R. [1 ]
Schneider, A. [2 ]
机构：
[1] Univ Zurich, Inst Vet Pharmakol & Toxikol, CH-8057 Zurich, Switzerland
[2] Schweizer Heilmittelinst, Bern, Switzerland
[3] IVI, Mittelhausern, Germany
[4] STIZ, Zurich, Switzerland
来源：
SCHWEIZER ARCHIV FUR TIERHEILKUNDE | 2009年 / 151卷 / 01期
关键词：
pharmacovigilance; vaccinovigilance; reconversion; residues; Delvo test; DRUG-REACTIONS; VACCINES; AMITRAZ;
D O I：
10.1024/0036-7281.151.1.12
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
163 reports of suspected adverse reactions were received in the year 2007: 111 for veterinary medicinal (VMPs) and 52 for immunologic products. Half of the reported reactions for VMPs concerned either an antiparasitic drug (26%) or an antibiotic (24%). Reconversions (use in another target species or for another indication as registered) made the third most frequently mentioned group with I I reports. For immunologicals, half of the declarations were related to an adverse reaction in dogs, the most frequently reported reaction in companion animals being allergies. Moreover, 272 enquiries were received by the Swiss Toxicological Information Center in Zurich. Most of these were related to dogs (73%) and the number of enquiries regarding VMPs correlated positively with the most frequently used therapeutic classes like anti-parasitics (47%) and anti-inflammatory drugs (23%). The complexity of proscessing reports regarding the detection of residues in milk after prescribed withdrawal times is discussed in detail. In conclusion, the year 2007 is seen as a consolidation of the established system with a tendency towards increase in the number of complex cases.
引用
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页码：12 / 20
页数：9
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