Primary Hypertension in Childhood

被引:42
作者
Bucher, Barbara S. [1 ,2 ]
Ferrarini, Alessandra [2 ,3 ]
Weber, Nico [1 ,2 ]
Bullo, Marina [1 ,2 ,3 ]
Bianchetti, Mario G. [2 ,3 ]
Simonetti, Giacomo D. [1 ,2 ]
机构
[1] Univ Bern, Inselspital, Univ Childrens Hosp, CH-3010 Bern, Switzerland
[2] Univ Bern, CH-3010 Bern, Switzerland
[3] Osped Reg Bellinzona & Valli, Dept Pediat, Bern, Switzerland
关键词
Arterial hypertension; Blood pressure; BP; Cardiovascular disease; Childhood; Children; Risk factors; Obesity; Essential; Primary; Tracking; Pathogenesis; Epidemiology; ELEVATED BLOOD-PRESSURE; CARDIOVASCULAR RISK-FACTORS; LEFT-VENTRICULAR GEOMETRY; URIC-ACID; BODY-SIZE; DEMOGRAPHIC CHARACTERISTICS; ARTERIAL STIFFNESS; RACIAL-DIFFERENCES; SALT SENSITIVITY; SECULAR TRENDS;
D O I
10.1007/s11906-013-0378-8
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
There is growing concern about elevated blood pressure in children and adolescents, because of its association with the obesity epidemic. Moreover, cardiovascular function and blood pressure level are determined in childhood and track into adulthood. Primary hypertension in childhood is defined by persistent blood pressure values a parts per thousand yen the 95th percentile and without a secondary cause. Preventable risk factors for elevated blood pressure in childhood are overweight, dietary habits, salt intake, sedentary lifestyle, poor sleep quality and passive smoking, whereas non-preventable risk factors include race, gender, genetic background, low birth weight, prematurity, and socioeconomic inequalities. Several different pathways are implicated in the development of primary hypertension, including obesity, insulin resistance, activation of the sympathetic nervous system, alterations in sodium homeostasis, renin-angiotensin system and altered vascular function. Prevention of adult cardiovascular disease should begin in childhood by regularly screening for high blood pressure, counseling for healthy lifestyle and avoiding preventable risk factors.
引用
收藏
页码:444 / 452
页数:9
相关论文
共 84 条
  • [1] Learning and Attention Problems Among Children With Pediatric Primary Hypertension
    Adams, Heather R.
    Szilagyi, Peter G.
    Gebhardt, Laura
    Lande, Marc B.
    [J]. PEDIATRICS, 2010, 126 (06) : E1425 - E1429
  • [2] Association of ACE Gene Insertion/Deletion Polymorphism With Birth Weight, Blood Pressure Levels, and ACE Activity in Healthy Children
    Ajala, Aline R.
    Almeida, Sandro S.
    Rangel, Marina
    Palomino, Zaira
    Strufaldi, Maria Wany L.
    Puccini, Rosana F.
    Araujo, Ronaldo C.
    Casarini, Dulce Elena
    Franco, Maria C. P.
    [J]. AMERICAN JOURNAL OF HYPERTENSION, 2012, 25 (07) : 827 - 832
  • [3] Low nephron number -: a new cardiovascular risk factor in children?
    Amann, K
    Plank, C
    Dötsch, J
    [J]. PEDIATRIC NEPHROLOGY, 2004, 19 (12) : 1319 - 1323
  • [4] Effects of Sleep Patterns and Obesity on Increases in Blood Pressure in a 5-Year Period: Report from the Tucson Children's Assessment of Sleep Apnea Study
    Archbold, Kristen Hedger
    Vasquez, Monica M.
    Goodwin, James L.
    Quan, Stuart F.
    [J]. JOURNAL OF PEDIATRICS, 2012, 161 (01) : 26 - 30
  • [5] Association between obesity and the severity of ambulatory hypertension in children and adolescents
    Babinska, Katarina
    Kovacs, Laszlo
    Janko, Viktor
    Dallos, Tomas
    Feber, Janusz
    [J]. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, 2012, 6 (05) : 356 - 363
  • [6] ESSENTIAL-HYPERTENSION PREDICTED BY TRACKING OF ELEVATED BLOOD-PRESSURE FROM CHILDHOOD TO ADULTHOOD - THE BOGALUSA HEART-STUDY
    BAO, WH
    THREEFOOT, SA
    SRINIVASAN, SR
    BERENSON, GS
    [J]. AMERICAN JOURNAL OF HYPERTENSION, 1995, 8 (07) : 657 - 665
  • [7] SERIAL CHANGES IN BLOOD-PRESSURE FROM ADOLESCENCE INTO ADULTHOOD
    BECKETT, LA
    ROSNER, B
    ROCHE, AF
    GUO, S
    [J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 1992, 135 (10) : 1166 - 1177
  • [8] Stimulus response of blood pressure in black and white young individuals helps explain racial divergence in adult cardiovascular disease: The Bogalusa Heart Study
    Berenson, Gerald S.
    Chen, Wei
    DasMahapatra, Pronabesh
    Fernandez, Camilo
    Giles, Thomas
    Xu, Jihua
    Srinivasan, Sathanur R.
    [J]. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, 2011, 5 (04) : 230 - 238
  • [9] Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults
    Berenson, GS
    Srinivasan, SR
    Bao, WH
    Newman, WP
    Tracy, RE
    Wattigney, WA
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (23) : 1650 - 1656
  • [10] Vitamin D and the cardiovascular system
    Beveridge, L. A.
    Witham, M. D.
    [J]. OSTEOPOROSIS INTERNATIONAL, 2013, 24 (08) : 2167 - 2180