The main approach to controlling epidemics of meningococcal meningitis in the African meningitis belt has been reactive vaccination campaigns with serogroup A polysaccharide vaccine once the outbreak reached an incidence threshold. Early reactive vaccination is effective in reducingmorbidity and mortality. A recent paper in International Health has shown that earlier reactive vaccination campaigns may be even more effective than increasing the coverage area of vaccination. Monovalent serogroup A conjugate vaccine programs have recently been launched to prevent transmission in endemic areas in the African meningitis belt. Conjugate vaccines can induce immunological memory and have impact on pharyngeal carriage. However, reactive vaccination still has a role to play taking into account the dynamic changes in the epidemiology of meningitis in this area.
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Inst Pasteur, Agence Med Prevent, F-75724 Paris 15, FranceInst Pasteur, Agence Med Prevent, F-75724 Paris 15, France
Lafourcade, Berthe-Marie Njanpop
Sanou, Oumarou
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Ctr Muraz, Agence Med Prevent, Bobo Dioulasso 01, Burkina FasoInst Pasteur, Agence Med Prevent, F-75724 Paris 15, France
Sanou, Oumarou
van der Linden, Mark
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Univ Hosp RWTH Aachen, Dept Med Microbiol, German Natl Reference Ctr Streptococci, D-52074 Aachen, GermanyInst Pasteur, Agence Med Prevent, F-75724 Paris 15, France
van der Linden, Mark
Levina, Natalia
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Univ Hosp RWTH Aachen, Dept Med Microbiol, German Natl Reference Ctr Streptococci, D-52074 Aachen, GermanyInst Pasteur, Agence Med Prevent, F-75724 Paris 15, France
Levina, Natalia
Karanfil, Meryem
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Univ Hosp RWTH Aachen, Dept Med Microbiol, German Natl Reference Ctr Streptococci, D-52074 Aachen, GermanyInst Pasteur, Agence Med Prevent, F-75724 Paris 15, France
Karanfil, Meryem
Yaro, Seydou
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机构:Inst Pasteur, Agence Med Prevent, F-75724 Paris 15, France
Yaro, Seydou
Tamekloe, Tsidi A.
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Minist Hlth Togo, Div Epidemiol, Lome, TogoInst Pasteur, Agence Med Prevent, F-75724 Paris 15, France
Tamekloe, Tsidi A.
Mueller, Judith E.
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Inst Pasteur, Agence Med Prevent, F-75724 Paris 15, FranceInst Pasteur, Agence Med Prevent, F-75724 Paris 15, France
机构:
Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USACtr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USA
Kobayashi, Miwako
Abdul-Karim, Abass
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Zonal Publ Hlth Lab, Tamale, GhanaCtr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USA
Abdul-Karim, Abass
Milucky, Jennifer L.
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Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USACtr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USA
Milucky, Jennifer L.
Zakariah, Adam
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Ghana Hlth Serv, Bulisa, GhanaCtr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USA
Zakariah, Adam
Leidner, Andrew J.
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Natl Ctr Immunizat & Resp Dis, Ctr Dis Control & Prevent, Immunizat Serv Div, Atlanta, GA USACtr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USA
Leidner, Andrew J.
Asiedu-Bekoe, Franklin
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Ghana Hlth Serv, Accra, GhanaCtr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USA
Asiedu-Bekoe, Franklin
Opare, David
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Ghana Hlth Serv, Accra, GhanaCtr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USA
Opare, David
Eleeza, John B.
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Ghana Hlth Serv, Tamale, GhanaCtr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USA
Eleeza, John B.
Ofosu, Winfred
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Ghana Hlth Serv, Bolgatanga, GhanaCtr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USA
Ofosu, Winfred
Walker, Chastity
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Ctr Global Hlth, Div Global Hlth Protect, Accra, GhanaCtr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USA
Walker, Chastity
Whitney, Cynthia G.
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Emory Univ, Rollins Sch Publ Hlth, Dept Global Hlth, Atlanta, GA USACtr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USA
Whitney, Cynthia G.
Lessa, Fernanda C.
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Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USACtr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Bacterial Dis, Atlanta, GA USA
机构:
Norwegian Inst Publ Hlth, WHO Collaborating Ctr Reference & Res Meningococc, Oslo, Norway
Univ Oslo, Fac Med, Oslo, NorwayNorwegian Inst Publ Hlth, WHO Collaborating Ctr Reference & Res Meningococc, Oslo, Norway
Caugant, Dominique A.
Kristiansen, Paul A.
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Norwegian Inst Publ Hlth, WHO Collaborating Ctr Reference & Res Meningococc, Oslo, NorwayNorwegian Inst Publ Hlth, WHO Collaborating Ctr Reference & Res Meningococc, Oslo, Norway
Kristiansen, Paul A.
Wang, Xin
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Ctr Dis Control & Prevent, WHO Collaborating Ctr Prevent & Control Epidem Me, Atlanta, GA USANorwegian Inst Publ Hlth, WHO Collaborating Ctr Reference & Res Meningococc, Oslo, Norway
Wang, Xin
Mayer, Leonard W.
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Ctr Dis Control & Prevent, WHO Collaborating Ctr Prevent & Control Epidem Me, Atlanta, GA USANorwegian Inst Publ Hlth, WHO Collaborating Ctr Reference & Res Meningococc, Oslo, Norway
Mayer, Leonard W.
Taha, Muhamed-Kheir
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Inst Pasteur, WHO Collaborating Ctr Reference & Res Meningococc, Paris, FranceNorwegian Inst Publ Hlth, WHO Collaborating Ctr Reference & Res Meningococc, Oslo, Norway
Taha, Muhamed-Kheir
Ouedraogo, Rasmata
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Ctr Hosp Univ Pediat Charles de Gaulle, Lab Reference Meningite, Ouagadougou, Burkina FasoNorwegian Inst Publ Hlth, WHO Collaborating Ctr Reference & Res Meningococc, Oslo, Norway
Ouedraogo, Rasmata
Kandolo, Denis
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WHO Inter Country Support Team W Africa, Ouagadougou, Burkina FasoNorwegian Inst Publ Hlth, WHO Collaborating Ctr Reference & Res Meningococc, Oslo, Norway
Kandolo, Denis
Bougoudogo, Flabou
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INRSP, Bamako, MaliNorwegian Inst Publ Hlth, WHO Collaborating Ctr Reference & Res Meningococc, Oslo, Norway
Bougoudogo, Flabou
Sow, Samba
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CVD, Bamako, MaliNorwegian Inst Publ Hlth, WHO Collaborating Ctr Reference & Res Meningococc, Oslo, Norway
Sow, Samba
Bonte, Laurence
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Med Sans Frontieres, Support Logist, Paris, FranceNorwegian Inst Publ Hlth, WHO Collaborating Ctr Reference & Res Meningococc, Oslo, Norway