Meningococcal meningitis: vaccination outbreak response and epidemiological changes in the African meningitis belt

被引:3
|
作者
Carod Artal, Francisco Javier [1 ,2 ]
机构
[1] Raigmore Hosp, Dept Neurol, Inverness IV2 3UJ, Scotland
[2] UIC, Barcelona, Spain
来源
INTERNATIONAL HEALTH | 2015年 / 7卷 / 04期
关键词
Conjugate vaccine; Meningitis surveillance; Neisseria meningitides; Polysaccharide vaccine; Serogroup A; Vaccination outbreak response; DISEASE; IMPACT;
D O I
10.1093/inthealth/ihv025
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The main approach to controlling epidemics of meningococcal meningitis in the African meningitis belt has been reactive vaccination campaigns with serogroup A polysaccharide vaccine once the outbreak reached an incidence threshold. Early reactive vaccination is effective in reducingmorbidity and mortality. A recent paper in International Health has shown that earlier reactive vaccination campaigns may be even more effective than increasing the coverage area of vaccination. Monovalent serogroup A conjugate vaccine programs have recently been launched to prevent transmission in endemic areas in the African meningitis belt. Conjugate vaccines can induce immunological memory and have impact on pharyngeal carriage. However, reactive vaccination still has a role to play taking into account the dynamic changes in the epidemiology of meningitis in this area.
引用
收藏
页码:226 / 227
页数:2
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