Predictors of walking capacity in peripheral arterial disease patients

被引:17
作者
Farah, Breno Quintella [1 ]
dos Anjos Souza Barbosa, Joao Paulo [2 ]
Cucato, Gabriel Grizzo [2 ]
Chehuen, Marcel da Rocha [2 ]
Gobbo, Luis Alberto [3 ]
Wolosker, Nelson [4 ]
de Moraes Forjaz, Claudia Lucia [2 ]
Ritti-Dias, Raphael Mendes [1 ]
机构
[1] Univ Fed Pernambuco, Sch Phys Educ, Recife, PE, Brazil
[2] Univ Sao Paulo, Sch Phys Educ & Sport, Exercise Hemodynam Lab, Sao Paulo, Brazil
[3] Univ Sao Paulo, Fac Publ Hlth, Sao Paulo, Brazil
[4] Univ Sao Paulo, Fac Med, Sao Paulo, Brazil
关键词
Intermittent Claudication; Peripheral Arterial Disease; Walking Prediction; Comorbidities; IMPAIRMENT QUESTIONNAIRE; ENDOTHELIAL DYSFUNCTION; FUNCTIONAL PERFORMANCE; CLAUDICATION; INFLAMMATION; VALIDATION; MORTALITY; FORCE; LIMBS;
D O I
10.6061/clinics/2013(04)16
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE: To estimate walking capacity in intermittent claudication patients through a prediction model based on clinical characteristics and the walking impairment questionnaire. METHODS: The sample included 133 intermittent claudication patients of both genders aged between 30 and 80 years. Data regarding clinical characteristics, the walking impairment questionnaire and treadmill walking test performance were obtained. Multiple regression modeling was conducted to predict claudication onset distance and total walking distance using clinical characteristics (age, height, mass, body mass index, ankle brachial index lower, gender, history of smoking and co-morbid conditions) and walking impairment questionnaire responses. Comparisons of claudication onset distance and total walking distance measured during treadmill tests and estimated by a regression equation were performed using paired t-tests. RESULTS: Co-morbid conditions (diabetes and coronary artery disease) and questions related to difficulty in walking short distances (walking indoors - such as around your house and walking 5 blocks) and at low speed (walking 1 block at average speed - usual pace) resulted in the development of new prediction models high significant for claudication onset distance and total walking distance (p < 0.001). In addition, non-significant differences from the results obtained by the treadmill test and estimated by the current model (p > 0.05) were observed. CONCLUSION: The current study demonstrated that walking capacity can be adequately estimated based on comorbid conditions and responses to the walking impairment questionnaire.
引用
收藏
页码:537 / 541
页数:5
相关论文
共 25 条
[1]   Multifactorial Determinants of Functional Capacity in Peripheral Arterial Disease Uncoupling of Calf Muscle Perfusion and Metabolism [J].
Anderson, Justin D. ;
Epstein, Frederick H. ;
Meyer, Craig H. ;
Hagspiel, Klaus D. ;
Wang, Hongkun ;
Berr, Stuart S. ;
Harthun, Nancy L. ;
Weltman, Arthur ;
DiMaria, Joseph M. ;
West, Amy M. ;
Kramer, Christopher M. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 54 (07) :628-635
[2]   Endothelial dysfunction: A key to the pathophysiology and natural history of peripheral arterial disease? [J].
Brevetti, Gregorio ;
Schiano, Vittorio ;
Chiariello, Massimo .
ATHEROSCLEROSIS, 2008, 197 (01) :1-11
[3]   Inflammation in Peripheral Artery Disease [J].
Brevetti, Gregorio ;
Giugliano, Giuseppe ;
Brevetti, Linda ;
Hiatt, William R. .
CIRCULATION, 2010, 122 (18) :1862-1875
[4]   In concomitant coronary and peripheral arterial disease, inflammation of the affected limbs predicts coronary artery endothelial dysfunction [J].
Brevetti, Gregorio ;
Piscione, Federico ;
Cirillo, Plinio ;
Galasso, Gennaro ;
Schiano, Vittorio ;
Barbato, Emanuele ;
Scopacasa, Francesco ;
Chiariello, Massimo .
ATHEROSCLEROSIS, 2008, 201 (02) :440-446
[5]   Type 2 diabetes mellitus worsens arterial stiffness in hypertensive patients through endothelial dysfunction [J].
Bruno, R. M. ;
Penno, G. ;
Daniele, G. ;
Pucci, L. ;
Lucchesi, D. ;
Stea, F. ;
Landini, L. ;
Cartoni, G. ;
Taddei, S. ;
Ghiadoni, L. ;
Del Prato, S. .
DIABETOLOGIA, 2012, 55 (06) :1847-1855
[6]  
Gardner A W, 1996, Vasc Med, V1, P91
[7]   Gender differences in daily ambulatory activity patterns in patients with intermittent claudication [J].
Gardner, Andrew W. ;
Parker, Donald E. ;
Montgomery, Polly S. ;
Khurana, Aman ;
Ritti-Dias, Raphael M. ;
Blevins, Steve M. .
JOURNAL OF VASCULAR SURGERY, 2010, 52 (05) :1204-1210
[8]  
GARDNER AW, 1991, MED SCI SPORT EXER, V23, P402
[9]  
Hirsch AT, 2006, CIRCULATION, V113, pE463, DOI 10.1161/CIRCULATIONAHA.106.174526
[10]   Relationship between objective measures of peripheral arterial disease severity to self-reported quality of life in older adults with intermittent claudication [J].
Izquierdo-Porrera, AM ;
Gardner, AW ;
Bradham, DD ;
Montgomery, PS ;
Sorkin, JD ;
Powell, CC ;
Katzel, LI .
JOURNAL OF VASCULAR SURGERY, 2005, 41 (04) :625-630