Association between obesity and gallbladder cancer

被引：24

作者：

Wang, Fei ^{[1
]}

Wang, Bingyuan ^{[1
]}

Qiao, Liang ^{[2
]}

机构：

[1] China Med Univ, Affiliated Hosp 1, Dept Gastroenterol, Shenyang 110001, Liaoning Provin, Peoples R China

[2] Univ Sydney, Westmead Hosp, Western Clin Sch, Storr Liver Unit,Westmead Millennium Inst, Westmead, NSW 2145, Australia

来源：

FRONTIERS IN BIOSCIENCE-LANDMARK | 2012年 / 17卷

关键词：

Body Mass Index; Cancer; Epidemiology; Gallbladder; Lifestyle Modification; Obesity; Review; BILIARY-TRACT CANCER; BODY-MASS INDEX; INSULIN-RESISTANCE; RISK-FACTORS; SYMPTOMATIC GALLSTONES; UNITED-STATES; DIET; STONES; EPIDEMIOLOGY; OVERWEIGHT;

D O I：

10.2741/4070

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Obesity has become a global health issue because of its increased morbidity and mortality, and a close association with at least 20 different cancers. Clinical and epidemiological studies have suggested that obesity and overweight are positively related with the risk of GBC. Gallbladder cancer (GBC) is a relatively infrequent but highly lethal neoplasm. Obesity may disturb lipid and endogenous hormones metabolism, affect gallbladder motility, increase the risk of gallstones, and thus plays a role in GBC. Control of obesity through measures such as lifestyle modification, healthy diet, and regular exercise may prove useful in the prevention of GBC.

引用

页码：2550 / 2558

页数：9

共 81 条

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